Suppr超能文献

对赌博成瘾者和阿片类药物成瘾者风险行为的评估。

Evaluation of Risk Behavior in Gambling Addicted and Opioid Addicted Individuals.

作者信息

Gorzelańczyk Edward J, Walecki Piotr, Błaszczyszyn Monika, Laskowska Ewa, Kawala-Sterniuk Aleksandra

机构信息

Department of Theoretical Basis of Bio-Medical Sciences and Medical Informatics, Nicolaus Copernicus University - Collegium Medicum, Bydgoszcz, Poland.

Institute of Philosophy, Kazimierz Wielki University, Bydgoszcz, Poland.

出版信息

Front Neurosci. 2021 Jan 7;14:597524. doi: 10.3389/fnins.2020.597524. eCollection 2020.

Abstract

Evidence suggests that both opioid addicted and gambling addicted individuals are characterized by higher levels of risky behavior in comparison to healthy people. It has been shown that the administration of substitution drugs can reduce cravings for opioids and the risky decisions made by individuals addicted to opioids. Although it is suggested that the neurobiological foundations of addiction are similar, it is possible that risk behaviors in opioid addicts may differ in detail from those addicted to gambling. The aim of this work was to compare the level of risk behavior in individuals addicted to opioid, with that of individuals addicted to gambling, using the Iowa Gambling Task (IGT). The score and response time during the task were measured. It was also observed, in the basis of the whole IGT test, that individuals addicted to gambling make riskier decisions in comparison to healthy individuals from the control group but less riskier decisions in comparison to individuals addicted to opioids, before administration of methadone and without any statistically significant difference after administration of methadone-as there has been growing evidence that methadone administration is strongly associated with a significant decrease in risky behavior.

摘要

有证据表明,与健康人相比,阿片类药物成瘾者和赌博成瘾者都表现出更高水平的冒险行为。研究表明,使用替代药物可以减少对阿片类药物的渴望以及阿片类药物成瘾者做出的冒险决策。尽管有人认为成瘾的神经生物学基础相似,但阿片类药物成瘾者的冒险行为在细节上可能与赌博成瘾者不同。这项研究的目的是使用爱荷华赌博任务(IGT)比较阿片类药物成瘾者和赌博成瘾者的冒险行为水平。测量了任务期间的得分和反应时间。基于整个IGT测试还观察到,与对照组的健康个体相比,赌博成瘾者做出的冒险决策更多,但与阿片类药物成瘾者相比,在服用美沙酮之前做出的冒险决策更少,且在服用美沙酮后没有任何统计学上的显著差异——因为越来越多的证据表明,服用美沙酮与冒险行为的显著减少密切相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/034b/7817611/dd775ef7f43a/fnins-14-597524-g0001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验