Piwowarek Kamil, Lipińska Edyta, Hać-Szymańczuk Elżbieta, Pobiega Katarzyna
Department of Food Biotechnology and Microbiology, Institute of Food Sciences, Warsaw University of Life Sciences-SGGW (WULS-SGGW), Nowoursynowska 159c Street, 02-776 Warsaw, Poland.
3 Biotech. 2021 Feb;11(2):60. doi: 10.1007/s13205-020-02582-x. Epub 2021 Jan 11.
Propionic acid and its salts are widely used as food and feed preservative. Currently, these compounds are chemically produced, which is more profitable compared to biotechnological production using bacteria of the genus. Appropriate steps can enable reducing the production costs; for example, cheap industrial byproducts can be used as culture media. One such cost-effective raw material is apple pomace, a low-value byproduct from the food industry. It contains sugars such as glucose and fructose which can serve as potential carbon sources for microorganisms. This paper discusses the possibility of using apple pomace in the production of propionic acid and presents an economic analysis of the production process. The tested strain produced 8.01 g/L of propionic acid (yield 0.40 g/g) and 2.29 g/L of acetic acid (yield 0.11 g/g) from apple pomace extract. The economic analysis showed that the production of 1 kg of propionic acid (considering only waste) from 1000 kg of apple pomace would cost approximately 1.25 USD. The manufacturing cost (consumables, including feedstock, labor, and utilities) would be approximately 2.35 USD/kg, and the total cost including taxes would be approximately 3.05 USD/kg. From the economic point of view, it is necessary to improve the production of propionic acid from apple pomace, to increase the yield of fermentation and thus decrease the total production costs. This can be achieved, for example, using industrial byproducts as nitrogen and vitamin sources, instead of high-cost substrates such as yeast extract or peptone.
The online version contains supplementary material available at 10.1007/s13205-020-02582-x.
丙酸及其盐类被广泛用作食品和饲料防腐剂。目前，这些化合物是通过化学方法生产的，与使用该属细菌的生物技术生产相比，化学生产更具利润。采取适当措施可以降低生产成本；例如，廉价的工业副产品可用作培养基。一种这样具有成本效益的原材料是苹果渣，它是食品工业的低价值副产品。它含有葡萄糖和果糖等糖类，可作为微生物的潜在碳源。本文讨论了在丙酸生产中使用苹果渣的可能性，并对生产过程进行了经济分析。测试菌株从苹果渣提取物中产生了8.01克/升的丙酸（产率0.40克/克）和2.29克/升的乙酸（产率0.11克/克）。经济分析表明，从1000千克苹果渣中生产1千克丙酸（仅考虑废弃物）的成本约为1.25美元。制造成本（消耗品，包括原料、劳动力和公用事业）约为2.35美元/千克，包括税收在内的总成本约为3.05美元/千克。从经济角度来看，有必要提高从苹果渣中生产丙酸的产量，提高发酵产率，从而降低总生产成本。这可以通过例如使用工业副产品作为氮源和维生素源，而不是使用酵母提取物或蛋白胨等高成本底物来实现。
在线版本包含可在10.1007/s13205-020-02582-x获取的补充材料。
