从一例复发性肉芽肿性乳腺炎病例中分离出的全基因组序列。
Whole genome sequence of isolated from a case of recurrent granulomatous mastitis.
作者信息
Tan Charlie, Lu Fang-I, Aftanas Patryk, Tsang Kara, Mubareka Samira, Chan Adrienne, Kozak Robert
机构信息
Division of Infectious Diseases, Department of Medicine, University of Toronto, Toronto, ON, Canada.
Division of Pathology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
出版信息
IDCases. 2020 Dec 29;23:e01034. doi: 10.1016/j.idcr.2020.e01034. eCollection 2021.
We describe the case of a 33-year-old woman with recurrent granulomatous mastitis associated with This organism has been increasingly associated with granulomatous mastitis, specifically the cystic neutrophilic histopathologic variant, although currently there is a paucity both of reported cases and genomic sequence data. We highlight the challenges in the diagnosis and treatment of this entity, in particular focusing on the various methods of microbiologic identification, including MALDI-TOF, 16 s rRNA PCR and whole-genome sequencing.
我们描述了一名33岁复发性肉芽肿性乳腺炎女性患者的病例，该病例与这种微生物有关。这种微生物越来越多地与肉芽肿性乳腺炎相关，特别是囊性中性粒细胞组织病理学变异型，尽管目前报道的病例和基因组序列数据都很匮乏。我们强调了诊断和治疗该疾病的挑战，尤其关注微生物鉴定的各种方法，包括基质辅助激光解吸电离飞行时间质谱（MALDI-TOF）、16s rRNA聚合酶链反应（PCR）和全基因组测序。
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