代谢综合征危险因素对儿童颈动脉内膜中层厚度的影响
The Influence of Metabolic Syndrome Risk Factors on Carotid Intima Media Thickness in Children.
作者信息
Downing Robert, Michael Timothy, Place Rebecca, Hoffman Eric, Visich Paul
机构信息
University of New England, Biddeford, ME, USA.
Western Michigan University, Kalamazoo, MI, USA.
出版信息
Glob Pediatr Health. 2021 Jan 11;8:2333794X20987453. doi: 10.1177/2333794X20987453. eCollection 2021.
Pediatric obesity is a major health concern today, which pre-disposes individuals to metabolic syndrome (MS), and the risk of premature cardiovascular disease (CVD). Use of carotid intima media thickness (CIMT) is recognized as non-invasive way to assess vascular health. The objective of this study was to determine which MBS risk factors has an influence on increasing one's risk of an increased CIMT in children. In southern Maine 189 children (age: 10.52 ± .52 years) had their MBS risk factors and CIMT assessed. Based on CIMT, children were divided into quartiles and compared to MBS risk factors. Children in the highest quartile for CIMT had the highest waist circumference ( < .05) compared to all other groups, using a one-way analysis of variance. No other MBS risk factors had an influence on CIMT. It appears early identification of children with an elevated WC may be beneficial in identifying children at risk of premature CVD.
小儿肥胖是当今主要的健康问题，它会使个体易患代谢综合征（MS）以及心血管疾病（CVD）过早发生的风险。使用颈动脉内膜中层厚度（CIMT）被认为是评估血管健康的非侵入性方法。本研究的目的是确定哪些代谢综合征风险因素会增加儿童CIMT升高的风险。在缅因州南部，对189名儿童（年龄：10.52±0.52岁）进行了代谢综合征风险因素和CIMT评估。根据CIMT，将儿童分为四分位数，并与代谢综合征风险因素进行比较。使用单因素方差分析，CIMT最高四分位数的儿童与所有其他组相比，腰围最高（P<0.05）。没有其他代谢综合征风险因素对CIMT有影响。看来，早期识别腰围升高的儿童可能有助于识别有过早发生心血管疾病风险的儿童。
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