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噪声污染暴露会影响 COVID-19 的发病率和严重程度吗?

Does exposure to noise pollution influence the incidence and severity of COVID-19?

机构信息

National School of Public Health, Carlos III Institute of Health (ISCIII), Madrid, Spain.

National School of Public Health, Carlos III Institute of Health (ISCIII), Madrid, Spain.

出版信息

Environ Res. 2021 Apr;195:110766. doi: 10.1016/j.envres.2021.110766. Epub 2021 Jan 23.

Abstract

Research that analyzes the effect of different environmental factors on the impact of COVID-19 focus primarily on meteorological variables such as humidity and temperature or on air pollution variables. However, noise pollution is also a relevant environmental factor that contributes to the worsening of chronic cardiovascular diseases and even diabetes. This study analyzes the role of short-term noise pollution levels on the incidence and severity of cases of COVID-19 in Madrid from February 1 to May 31, 2020. The following variables were used in the study: daily noise levels averaged over 14 days; daily incidence rates, average cumulative incidence over 14 days; hospital admissions, Intensive Care Unit (ICU) admissions and mortality due to COVID-19. We controlled for the effect of the pollutants PM and NO as well as for variables related to seasonality and autoregressive nature. GLM models with Poisson regressions were carried out using significant variable selection (p < 0.05) to calculate attributable RR. The results of the modeling using a single variable show that the levels of noise (leq24 h) were related to the incidence rate, the rate of hospital admissions, the ICU admissions and the rate of average cumulative incidence over 14 days. These associations presented lags, and the first association was with incidence (lag 7 and lag 10), then with hospital admissions (lag 17) and finally ICU admissions (lag 22). There was no association with deaths due to COVID-19. In the results of the models that included PM1, NO, Leq24 h and the control variables simultaneously, we observed that only Leq24 h went on to become a part of the models using COVID-19 variables, including the 14-day average cumulative incidence. These results show that noise pollution is an important environmental variable that is relevant in relation to the incidence and severity of COVID-19 in the Province of Madrid.

摘要

这项研究分析了短期噪声污染水平对 2020 年 2 月 1 日至 5 月 31 日马德里 COVID-19 病例发生和严重程度的影响。研究中使用了以下变量:14 天内的日平均噪声水平;每日发病率,14 天内的平均累积发病率;因 COVID-19 住院、入住重症监护病房(ICU)和死亡的人数。我们控制了 PM 和 NO 污染物的影响,以及与季节性和自回归性质相关的变量。使用具有显著变量选择(p<0.05)的广义线性模型(GLM)进行泊松回归,以计算归因 RR。使用单一变量进行建模的结果表明,噪声(leq24 h)水平与发病率、住院率、ICU 入住率和 14 天内的平均累积发病率有关。这些关联存在滞后,第一个关联是与发病率(滞后 7 天和滞后 10 天),然后是与住院率(滞后 17 天),最后是与 ICU 入住率(滞后 22 天)。与 COVID-19 死亡人数没有关联。在同时包含 PM1、NO、Leq24 h 和控制变量的模型结果中,我们观察到仅 Leq24 h 继续成为包含 COVID-19 变量的模型的一部分,包括 14 天的平均累积发病率。这些结果表明,噪声污染是一个重要的环境变量,与马德里省 COVID-19 的发病率和严重程度有关。

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