中国 49 个城市中颗粒物污染与 COVID-19 病死率的关系。
Association of particulate matter pollution and case fatality rate of COVID-19 in 49 Chinese cities.
机构信息
School of Public Health, Fudan University, Shanghai, China.
School of Public Health, Fudan University, Shanghai, China; Key Laboratory of Public Health Safety of Ministry of Education, Fudan University, Shanghai, China.
出版信息
Sci Total Environ. 2020 Nov 1;741:140396. doi: 10.1016/j.scitotenv.2020.140396. Epub 2020 Jun 20.
The COVID-19 epidemic, caused by the SARS-CoV-2 virus, has resulted in 3352 deaths in China as of April 12, 2020. This study aimed to investigate the associations between particulate matter (PM) concentrations and the case fatality rate (CFR) of COVID-19 in 49 Chinese cities, including the epicenter of Wuhan. We used the Global Moran's I to analyze spatial distribution and autocorrelation of CFRs, and then we used multivariate linear regression to analyze the associations between PM and PM concentrations and COVID-19 CFR. We found positive associations between PM pollution and COVID-19 CFR in cities both inside and outside Hubei Province. For every 10 μg/m increase in PM and PM concentrations, the COVID-19 CFR increased by 0.24% (0.01%-0.48%) and 0.26% (0.00%-0.51%), respectively. PM pollution distribution and its association with COVID-19 CFR suggests that exposure to such may affect COVID-19 prognosis.
截至 2020 年 4 月 12 日，由 SARS-CoV-2 病毒引起的 COVID-19 疫情已导致中国 3352 人死亡。本研究旨在调查中国 49 个城市（包括武汉疫区）的颗粒物（PM）浓度与 COVID-19 病死率（CFR）之间的关系。我们使用全局 Moran's I 分析了 CFR 的空间分布和自相关，然后使用多元线性回归分析了 PM 和 PM 浓度与 COVID-19 CFR 之间的关系。我们发现，在湖北省内外城市中，PM 污染与 COVID-19 CFR 之间呈正相关关系。PM 和 PM 浓度每增加 10μg/m，COVID-19 CFR 分别增加 0.24%（0.01%-0.48%）和 0.26%（0.00%-0.51%）。PM 污染的分布及其与 COVID-19 CFR 的关系表明，暴露于这种污染可能会影响 COVID-19 的预后。
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