Herrera J L, Simpson J K, Maydonovitch C L, Wong R K
Department of Medicine, Walter Reed Army Medical Center, Washington, D.C. 20307-5001.
Dig Dis Sci. 1988 Apr;33(4):385-8. doi: 10.1007/BF01536018.
Twenty-four-hour pH monitoring of the esophagus is frequently performed to assess gastroesophageal reflux. We performed a prospective study to determine if results obtained from stationary and ambulatory pH recording systems are comparable. Two groups of patients were studied. Group I consisted of 12 patients monitored simultaneously by both a stationary and an ambulatory pH recording system, each system having a separate pH and reference electrode. In group II, in order to eliminate electrode variability, 10 patients were monitored simultaneously with both systems and a common single pH and reference electrode. In group I, significant correlations were found in six reflux parameters measured and in the 24-hr composite score (r greater than or equal to 0.8722). However, in three of the 12 patients, marked discrepancies were noted in the composite score calculated by the stationary and ambulatory recording systems. Small variations in the pH level recorded by different pH electrodes may have accounted for the discrepancies. In group II, where electrode variability was eliminated, a better correlation was noted between all parameters measured (r greater than or equal to 0.991), and no discrepancies were noted between calculated composite scores. We concluded that the stationary and ambulatory recording systems tested are comparable in measuring 24-hr esophageal pH.
经常进行食管24小时pH监测以评估胃食管反流。我们进行了一项前瞻性研究,以确定固定和动态pH记录系统所获得的结果是否具有可比性。对两组患者进行了研究。第一组由12名患者组成,他们同时使用固定和动态pH记录系统进行监测,每个系统都有单独的pH电极和参比电极。在第二组中,为了消除电极变异性,对10名患者同时使用两个系统和一个共用的单一pH电极及参比电极进行监测。在第一组中,所测量的六个反流参数和24小时综合评分之间发现了显著相关性(r大于或等于0.8722)。然而,在12名患者中的3名患者中,固定和动态记录系统计算出的综合评分存在明显差异。不同pH电极记录的pH水平的微小变化可能是造成这些差异的原因。在消除了电极变异性的第二组中,所有测量参数之间的相关性更好(r大于或等于0.991),并且计算出的综合评分之间没有差异。我们得出结论,所测试的固定和动态记录系统在测量24小时食管pH方面具有可比性。