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孕妇对某些国家流感疾病和疫苗接种实践的看法。

What do pregnant women think about influenza disease and vaccination practices in selected countries.

机构信息

Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Queen Sirikit National Institute of Child Health, Thailand Ministry of Public Health, Bangkok, Thailand.

出版信息

Hum Vaccin Immunother. 2021 Jul 3;17(7):2176-2184. doi: 10.1080/21645515.2020.1851536. Epub 2021 Jan 26.

Abstract

: We evaluated knowledge, attitudes, and practices (KAP) related to influenza and influenza vaccination among pregnant women in three selected countries.: During 2017, pregnant women seeking antenatal care at hospitals at participating sites were enrolled. We described characteristics and responses to KAP questions. We also evaluated predictors associated with influenza vaccination during pregnancy at sites with substantial influenza vaccine uptake by multivariable logistic regression.: Overall, 4,648 pregnant women completed the survey. There were substantial differences among the three survey populations; only 8% of the women in Nagpur had heard of influenza, compared to 90% in Lima and 96% in Bangkok (-value<0.01). Despite significant differences in sociodemographic characteristics in the three populations, most participants across sites who were aware of influenza prior to study enrollment believe they and their infants are at risk of influenza and related complications and believe influenza vaccination is safe and effective. Half of women in Lima had verified receipt of influenza vaccine compared to <5% in Bangkok and Nagpur ( < .05). For further analysis conducted among women in Lima only, household income above the poverty line (aOR: 1.38; 95%CI: 1.01, 1.88), having 8+ antenatal visits, compared to 0-4 (aOR: 2.41; 95%CI: 1.39, 2.87, respectively), having 0 children, compared to 2+ (aOR: 1.96; 95%CIs: 1.23, 3.12), and vaccination recommended by a health-care provider (aOR: 8.25; 95%CI: 6.11, 11.14) were strongly associated with receipt of influenza vaccine during pregnancy.: Our findings identify opportunities for targeted interventions to improve influenza vaccine uptake among pregnant women in these settings.

摘要

我们评估了三个选定国家的孕妇对流感和流感疫苗接种的知识、态度和实践(KAP)。2017 年,在参与地点的医院接受产前护理的孕妇参与了研究。我们描述了特征和对 KAP 问题的回答。我们还通过多变量逻辑回归评估了与这些地点有大量流感疫苗接种相关的与怀孕期间流感疫苗接种相关的预测因素。

总体而言,有 4648 名孕妇完成了调查。三个调查人群之间存在很大差异;只有 8%的那格浦尔孕妇听说过流感,而利马和曼谷的这一比例分别为 90%和 96%(P 值<0.01)。尽管三个人群的社会人口特征存在显著差异,但大多数在研究入组前就知道流感的参与者认为自己和婴儿有患流感和相关并发症的风险,并且认为流感疫苗接种是安全有效的。与曼谷和那格浦尔相比,利马有一半的女性已确认接种流感疫苗,而这两个地方的这一比例均<5%(P<0.05)。仅对利马的女性进行了进一步分析,家庭收入高于贫困线(OR:1.38;95%CI:1.01,1.88),与 0-4 次产前就诊(OR:2.41;95%CI:1.39,2.87)相比,就诊 8+次(OR:1.96;95%CI:1.23,3.12),以及与有 2+个以上孩子(OR:1.96;95%CI:1.23,3.12)相比,孩子为 0,以及卫生保健提供者推荐接种疫苗(OR:8.25;95%CI:6.11,11.14)与怀孕期间接种流感疫苗密切相关。

我们的研究结果确定了在这些环境中针对孕妇的目标干预措施,以提高流感疫苗接种率的机会。

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