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轮状病毒腹泻及其在印度哈里亚纳邦南部一家三级护理医院就诊的五岁以下儿童中的决定因素。

Rotavirus Diarrhea and its Determinants Among Under-Five Children Admitted in a Tertiary Care Hospital of Southern Haryana, India.

机构信息

Department of Pediatrics, All India Institute of Medical Sciences, Raipur, India.

Department of Community Medicine, Shaheed Hasan Khan Mewati Government Medical College, Nalhar, Nuh, Haryana, 122107, India.

出版信息

Indian J Pediatr. 2021 Mar;88(Suppl 1):16-21. doi: 10.1007/s12098-020-03616-1. Epub 2021 Jan 27.

DOI:10.1007/s12098-020-03616-1
PMID:33501607
Abstract

OBJECTIVE

To estimate the prevalence of rotavirus diarrhea and its demographic, social, and clinical characteristics among children less than five years of age admitted in a rural tertiary care institute.

METHODS

This prospective hospital-based observational study was carried out during February 2016 to June 2019. Diarrheal admissions of children aged 0-59 mo were screened and those who met the inclusion criteria were included in the study. Sociodemographic and clinical information was collected using a case report form. Stool samples were collected within 48 h of admission and transported in cold chain every month to the referral laboratory situated at Christian Medical College for testing.

RESULTS

Among the children admitted with acute diarrhea, 148 (11.02%) were positive for rotavirus in the study. As per Vesikari scoring system, around three fourth (76.2%) of children were having severe or very severe diarrhea. Severity of diarrhea was more among rotavirus positive cases as assessed by the Vesikari scoring system. The rotavirus diarrhea showed a peak during November to February.

CONCLUSION

Rotavirus diarrhea is an issue of public health importance, particularly due to its association with the severe diarrhea. As evidenced from similar settings in the world, rotavirus vaccine introduction and increased coverage is the most important strategy towards prevention and control of rotavirus diarrhea.

摘要

目的

评估农村三级保健机构收治的 5 岁以下儿童轮状病毒腹泻的流行率及其人口统计学、社会和临床特征。

方法

本前瞻性医院观察性研究于 2016 年 2 月至 2019 年 6 月进行。筛选 0-59 月龄腹泻住院患儿,符合纳入标准的患儿纳入研究。使用病例报告表收集社会人口统计学和临床信息。粪便样本在入院后 48 小时内采集,并每月在冷链中运送到位于基督教医学院的转诊实验室进行检测。

结果

在急性腹泻住院的儿童中,148 例(11.02%)轮状病毒检测阳性。根据 Vesikari 评分系统,约四分之三(76.2%)的儿童患有严重或非常严重的腹泻。轮状病毒阳性病例的腹泻严重程度更高,根据 Vesikari 评分系统评估。轮状病毒腹泻在 11 月至 2 月间呈高发。

结论

轮状病毒腹泻是一个重要的公共卫生问题,特别是因为它与严重腹泻有关。从世界上类似的情况来看,轮状病毒疫苗的引入和覆盖率的提高是预防和控制轮状病毒腹泻最重要的策略。

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本文引用的文献

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Seasonality of rotavirus in South Asia: a meta-analysis approach assessing associations with temperature, precipitation, and vegetation index.南亚轮状病毒的季节性:一项荟萃分析方法,评估与温度、降水和植被指数的关联。
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乌干达坎帕拉市用于治疗腹泻和咳嗽的草药。
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