Department of Pediatrics, RNT Medical College, Udaipur, Rajasthan, 313001, India.
The Wellcome Trust Research Laboratory, Christian Medical College (CMC), Vellore, Tamil Nadu, India.
Indian J Pediatr. 2021 Mar;88(Suppl 1):105-111. doi: 10.1007/s12098-020-03626-z. Epub 2021 Feb 2.
To determine the epidemiology of rotavirus diarrhea and its genotypes distribution among under five children from Udaipur, Rajasthan.
Hospital-based prospective study among children aged 0-59 mo of age hospitalized due to acute gastroenteritis and assess the clinical and epidemiological profile. Stool samples collected during 2017-2019 from 734 children, were tested by enzyme immune assay (EIA) to identify rotavirus and the samples that were positive were subjected to genotyping using published methods.
Rotavirus was detected in 12.94% (95/734) of the stool samples. Maximum positivity (38.9%) was seen in children aged 12-23 mo followed by 34.7% in 6-11 mo of age. Detection rates were higher (46.31%, 44/95) during winter months of December-February; 65% children with rotavirus diarrhea had severe dehydration followed by moderate dehydration in 32% of cases. G3P[8] (40, 43.01%) was the commonest genotype followed by G9P[4] (10, 10.75%).
Among under-five children hospitalized due to acute gastroenteritis in a tertiary care setting in Udaipur, Rajasthan, 12.9% of children were rotavirus positive with predominant (43.01%) circulation of G3P[8] strains.
确定拉贾斯坦邦乌代浦五岁以下儿童轮状病毒腹泻的流行病学及其基因型分布。
对 2017-2019 年因急性胃肠炎住院的 0-59 月龄儿童进行基于医院的前瞻性研究，评估其临床和流行病学特征。收集 734 名儿童的粪便样本，采用酶联免疫吸附试验（EIA）检测轮状病毒，对阳性样本采用已发表的方法进行基因分型。
在 734 份粪便样本中，检测到 12.94%（95/734）的轮状病毒。年龄在 12-23 月龄的儿童中阳性率最高（38.9%），其次为 6-11 月龄（34.7%）。12 月至 2 月的冬季检测率较高（46.31%，44/95）；65%轮状病毒腹泻患儿出现严重脱水，其次为 32%中度脱水。最常见的基因型是 G3P[8]（40 株，占 43.01%），其次是 G9P[4]（10 株，占 10.75%）。
在拉贾斯坦邦乌代浦的一家三级护理中心，因急性胃肠炎住院的五岁以下儿童中，12.9%的患儿轮状病毒检测阳性，主要（43.01%）流行 G3P[8]株。
