植物提取物对脂氧合酶的抑制作用。
Lipoxygenase Inhibition by Plant Extracts.
机构信息
Faculty of Food Technology Osijek, Josip Juraj Strossmayer University of Osijek, Franje Kuhaca 18, 31000 Osijek, Croatia.
Department of Biology, Josip Juraj Strossmayer University of Osijek, Ulica cara Hadrijana 8/A, 31000 Osijek, Croatia.
出版信息
Biomolecules. 2021 Jan 25;11(2):152. doi: 10.3390/biom11020152.
Abstract
Lipoxygenases are widespread enzymes that catalyze oxidation of polyunsaturated fatty acids (linoleic, linolenic, and arachidonic acid) to produce hydroperoxides. Lipoxygenase reactions can be desirable, but also lipoxygenases can react in undesirable ways. Most of the products of lipoxygenase reactions are aromatic compounds that can affect food properties, especially during long-term storage. Lipoxygenase action on unsaturated fatty acids could result in off-flavor/off-odor development, causing food spoilage. In addition, lipoxygenases are present in the human body and play an important role in stimulation of inflammatory reactions. Inflammation is linked to many diseases, such as cancer, stroke, and cardiovascular and neurodegenerative diseases. This review summarized recent research on plant families and species that can inhibit lipoxygenase activity.
摘要
脂氧合酶是广泛存在的酶，可催化多不饱和脂肪酸（亚油酸、亚麻酸和花生四烯酸）氧化生成氢过氧化物。脂氧合酶反应可能是可取的，但脂氧合酶也可能以不可取的方式反应。脂氧合酶反应的大多数产物是芳香族化合物，会影响食物特性，特别是在长期储存期间。脂氧合酶对不饱和脂肪酸的作用可能导致异味/异味的产生，导致食物变质。此外，脂氧合酶存在于人体中，在刺激炎症反应中发挥重要作用。炎症与许多疾病有关，如癌症、中风以及心血管和神经退行性疾病。本文综述了最近关于能够抑制脂氧合酶活性的植物科和种的研究。
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