Szary Cezary, Wilczko Justyna, Plucinska Dominika, Pachuta Anna, Napierala Marcin, Bodziony Anna, Zawadzki Michal, Leszczynski Jerzy, Galazka Zbigniew, Grzela Tomasz
Clinic of Phlebology, 02-034 Warsaw, Poland.
Diagnostic Imaging Center MRI & CT, Center of Sport Medicine, 02-034 Warsaw, Poland.
J Clin Med. 2021 Jan 25;10(3):455. doi: 10.3390/jcm10030455.
The current treatment of venous disease is focused on reflux elimination in main venous trunks, especially in the saphenous vein. However, a high recurrence rate, independent of the method of treatment, suggests that the reason of low effectiveness may be due to a strategy focused on symptoms, without considering their origin.
The aim of study was the comparison of retrospective data from 535 women with venous disease, either after treatment ( = 183) or not treated before ( = 352). The analysis concerned clinical symptoms and the results of the extended diagnostics, including the examination of the lower limb, pelvic and abdominal veins either using duplex-doppler ultrasound as well as venography with computed tomography or magnetic resonance.
The comparison of selected venous system parameters revealed more advanced disease progression in previously treated patients, compared to non-treated individuals (e.g., ipsi- or bilateral incompetence of sapheno-phemoral junction-29.5% vs. 20.4%, at < 0.05 and 13.6% vs. 7.7% at < 0.05, respectively). This difference could be explained by post-treatment alterations in the venous system, an older age and the higher number of pregnancies in the recurrence group. However, both groups did not differ in regards to the symptoms of pelvic venous insufficiency or the frequency of relevant variants/abnormalities in venous system.
Based on the aforementioned findings, we postulate the revision of treatment strategy, which should consider abdominal and pelvic veins as the source of reflux in many female subjects.
目前静脉疾病的治疗重点是消除主要静脉主干尤其是大隐静脉中的反流。然而,无论采用何种治疗方法,复发率都很高,这表明疗效不佳的原因可能是治疗策略侧重于症状,而未考虑其根源。
本研究旨在比较535例静脉疾病女性患者的回顾性数据,其中183例接受过治疗,352例未接受过治疗。分析涉及临床症状以及扩展诊断结果,包括使用双功多普勒超声以及计算机断层扫描或磁共振静脉造影对下肢、盆腔和腹部静脉进行检查。
所选静脉系统参数的比较显示,与未治疗的个体相比,先前接受过治疗的患者疾病进展更为严重(例如,大隐静脉股静脉交界处同侧或双侧功能不全——分别为29.5%对20.4%,P<0.05;以及13.6%对7.7%,P<0.05)。这种差异可以通过静脉系统的治疗后改变、复发组患者年龄较大以及妊娠次数较多来解释。然而,两组在盆腔静脉功能不全症状或静脉系统相关变异/异常的频率方面并无差异。
基于上述发现,我们建议修订治疗策略,该策略应将腹部和盆腔静脉视为许多女性患者反流的源头。