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第五届国际新生儿和孕产妇免疫接种研讨会(INMIS 2019):为下一代保驾护航。

The Fifth International Neonatal and Maternal Immunization Symposium (INMIS 2019): Securing Protection for the Next Generation.

机构信息

Vaccine Evaluation Center, BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada

Division of Infectious Diseases, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.

出版信息

mSphere. 2021 Jan 27;6(1):e00862-20. doi: 10.1128/mSphere.00862-20.

Abstract

Despite significant progress in reaching some milestones of the United Nations Sustainable Development Goals, neonatal and early infant morbidity and mortality remain high, and maternal health remains suboptimal in many countries. Novel and improved preventative strategies with the potential to benefit pregnant women and their infants are needed, with maternal and neonatal immunization representing effective approaches. Experts from immunology, vaccinology, infectious diseases, clinicians, industry, public health, and vaccine-related social sciences convened at the 5th International Neonatal and Maternal Immunization Symposium (INMIS) in Vancouver, Canada, from 15 to 17 September 2019. We critically evaluated the lessons learned from recent clinical studies, presented cutting-edge scientific progress in maternal and neonatal immunology and vaccine development, and discussed maternal and neonatal immunization in the broader context of infectious disease epidemiology and public health. Focusing on practical aspects of research and implementation, we also discussed the safety, awareness, and perception of maternal immunization as an existing strategy to address the need to improve maternal and neonatal health worldwide. The symposium provided a comprehensive scientific and practical primer as well as an update for all those with an interest in maternal and neonatal infection, immunity, and vaccination. The summary presented here provides an update of the current status of progress in maternal and neonatal immunization.

摘要

尽管在实现联合国可持续发展目标的一些里程碑方面取得了重大进展,但新生儿和婴儿早期发病率和死亡率仍然很高,许多国家的孕产妇健康状况仍不理想。需要新的和改进的预防策略,这些策略有可能使孕妇及其婴儿受益,孕产妇和新生儿免疫接种就是有效的方法。来自免疫学、疫苗学、传染病学、临床医生、工业界、公共卫生和与疫苗相关的社会科学领域的专家于 2019 年 9 月 15 日至 17 日在加拿大温哥华举行了第 5 届国际新生儿和孕产妇免疫接种研讨会(INMIS)。我们从最近的临床研究中吸取了经验教训,介绍了孕产妇和新生儿免疫学及疫苗开发方面的最新科学进展,并在传染病流行病学和公共卫生的更广泛背景下讨论了孕产妇和新生儿免疫接种问题。我们专注于研究和实施的实际方面,还讨论了孕产妇免疫接种作为一种现有策略的安全性、意识和看法,以解决全世界改善孕产妇和新生儿健康的需求。该研讨会为所有对孕产妇和新生儿感染、免疫和接种感兴趣的人提供了全面的科学和实用基础,并提供了最新信息。这里提供的总结更新了孕产妇和新生儿免疫接种的最新进展情况。

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