University of Campinas, School of Food Engineering, Rua Monteiro Lobato, 80, Zip Code 13083-862, Campinas/SP, Brazil.
Thrombosis Research Center, Medical Technology School, Department of Clinical Biochemistry and Immunohaematology, Faculty of Health Sciences, Universidad de Talca, Talca, 2 norte 685, Talca, Chile.
Food Res Int. 2021 Jan;139:109844. doi: 10.1016/j.foodres.2020.109844. Epub 2020 Oct 27.
Non-communicable diseases (NCDs) have been rapidly increasing; among them, cardiovascular diseases (CVDs) are responsible for around 1/3 of deaths in the world. Environmental factors play a central role in their development. Diet is a very important factor in this scenario, and the intake of fruits and vegetables has been considered as one of the critical strategies for reducing the risk of CVDs. Fruits are a source of micronutrients and bioactive compounds that could have cardioprotective effects through several distinct mechanisms, such as antioxidant, antithrombotic and antiplatelet activities, vasodilatation, improvement of plasma lipid profiles, and modulation of inflammatory signaling. Brazil has a very rich and unexplored biodiversity in its different biomes, with several types of fruit, which are a source of bioactive compounds and micronutrients with therapeutic properties. In this sense, this review shows the current knowledge regarding the cardioprotective properties of selected Latin American and Brazilian fruits, including their effects on the activation of platelets and on the inflammation processes involved in atherosclerosis and cardiovascular diseases.
非传染性疾病（NCDs）迅速增加；其中，心血管疾病（CVDs）占世界上约三分之一的死亡人数。环境因素在其发展中起着核心作用。饮食是这种情况下非常重要的因素，水果和蔬菜的摄入被认为是降低 CVD 风险的关键策略之一。水果是微量营养素和生物活性化合物的来源，通过几种不同的机制具有心脏保护作用，例如抗氧化、抗血栓和抗血小板活性、血管舒张、改善血浆脂质谱以及调节炎症信号。巴西在其不同生物群落中拥有非常丰富和未被开发的生物多样性，拥有多种水果，这些水果是具有治疗特性的生物活性化合物和微量营养素的来源。从这个意义上说，本综述展示了关于选定的拉丁美洲和巴西水果的心脏保护特性的现有知识，包括它们对血小板激活以及动脉粥样硬化和心血管疾病中涉及的炎症过程的影响。
