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老年痴呆患者的口腔健康状况:一项病例对照研究。

Oral Health Status in Older People with Dementia: A Case-Control Study.

作者信息

Lopez-Jornet Pia, Zamora Lavella Carmen, Pons-Fuster Lopez Eduardo, Tvarijonaviciute Asta

机构信息

Department Stomatology School of Medicine, Biomedical Research Institute (IMIB-Arrixaca), Faculty of Medicine and Odontology, University of Murcia, Adv Marques de los Velez s/n, 30008 Murcia, Spain.

Colaborate Oral Medicine, Faculty of Medicine and Odontology, University of Murcia, 30008 Murcia, Spain.

出版信息

J Clin Med. 2021 Jan 27;10(3):477. doi: 10.3390/jcm10030477.

DOI:10.3390/jcm10030477
PMID:33514062
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7865865/
Abstract

Dementia is characterized by a range of cognitive defects with impaired activities of daily living that have implications for patient oral health. Objectives. A case-control study was made of the impact of dementia upon oral health. A total of 152 patients were included: 69 with dementia and 83 controls from the region of Murcia (Spain). The Global Deterioration Scale (GDS) was used to classify the patients and an oral exploration was carried out. Odds ratios (ORs) and confidence intervals (CIs) were estimated using regression models. The patients with more severe disease were significantly more likely to have fewer natural teeth (OR 11.00, 95%CI 1.28-23.22; = 0.001), a higher plaque index ( = 0.001), and a greater bleeding index ( = 0.001) than the control group. These findings suggest that older adults with dementia have deficient oral health. A higher bleeding index increases the risk of deterioration of cognitive function. The oral hygiene and health of older people with dementia need to be improved.

摘要

痴呆症的特征是一系列认知缺陷以及日常生活活动受损,这对患者的口腔健康有影响。目的。开展一项病例对照研究,以探讨痴呆症对口腔健康的影响。共纳入152名患者:69名患有痴呆症,83名来自西班牙穆尔西亚地区的对照者。使用总体衰退量表(GDS)对患者进行分类,并进行口腔检查。使用回归模型估计比值比(OR)和置信区间(CI)。与对照组相比,病情较重的患者天然牙数量明显更少(OR 11.00,95%CI 1.28 - 23.22;P = 0.001),菌斑指数更高(P = 0.001),出血指数更大(P = 0.001)。这些发现表明,患有痴呆症的老年人口腔健康状况不佳。更高的出血指数会增加认知功能恶化的风险。痴呆症老年人的口腔卫生和健康状况需要改善。

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本文引用的文献

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Tooth Loss and Dementia: A Critical Examination.牙齿缺失与痴呆:批判性审视
J Dent Res. 2021 Mar;100(3):226-231. doi: 10.1177/0022034520957233. Epub 2020 Sep 18.
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Retrospective analysis of the association between tooth loss and dementia: a population-based matched case-control study.牙齿缺失与痴呆症关联的回顾性分析:一项基于人群的配对病例对照研究。
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The Association between Tooth Loss and Alzheimer's Disease: a Systematic Review with Meta-Analysis of Case Control Studies.牙齿缺失与阿尔茨海默病之间的关联:一项对病例对照研究的系统评价与荟萃分析
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Tooth Loss Increases the Risk of Diminished Cognitive Function: A Systematic Review and Meta-analysis.牙齿缺失会增加认知功能减退的风险:一项系统评价与荟萃分析
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Tooth Loss-associated Cognitive Impairment in the Elderly: A Community-based Study in Japan.老年人牙齿缺失相关的认知障碍:日本一项基于社区的研究
Intern Med. 2019 May 15;58(10):1411-1416. doi: 10.2169/internalmedicine.1896-18. Epub 2019 Jan 10.
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Tooth Loss Is Associated With Increased Risk of Dementia and With a Dose-Response Relationship.牙齿缺失与痴呆风险增加及剂量反应关系相关。
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Tooth loss as a risk factor for dementia: systematic review and meta-analysis of 21 observational studies.牙齿缺失是痴呆的危险因素:21 项观察性研究的系统评价和荟萃分析。
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