Development and Neurodiversity Lab, Department of Psychology, Uppsala University, Box 1225, 75142, Uppsala, Sweden.
Center of Neurodevelopmental Disorders (KIND), Centre for Psychiatry Research, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
J Autism Dev Disord. 2021 Nov;51(11):4186-4198. doi: 10.1007/s10803-021-04876-2. Epub 2021 Jan 30.
In typical development, infants form predictions about future events based on incoming sensory information, which is essential for perception and goal-directed action. It has been suggested that individuals with autism spectrum disorder (ASD) make predictions differently compared to neurotypical individuals. We investigated how infants who later received an ASD diagnosis and neurotypical infants react to temporarily occluded moving objects that violate initial expectations about object motion. Our results indicate that infants regardless of clinical outcome react similarly to unexpected object motion patterns, both in terms of gaze shift latencies and pupillary responses. These findings indicate that the ability to update representations about such regularities in light of new information may not differ between typically developing infants and those with later ASD.
在典型的发展过程中，婴儿基于传入的感觉信息形成对未来事件的预测，这对于感知和目标导向的行动至关重要。有研究表明，自闭症谱系障碍（ASD）患者与神经典型个体的预测方式不同。我们研究了后来被诊断为 ASD 的婴儿和神经典型婴儿如何对暂时遮挡的移动物体做出反应，这些物体违反了关于物体运动的初始预期。我们的结果表明，无论临床结果如何，婴儿对意想不到的物体运动模式的反应相似，无论是在注视潜伏期还是瞳孔反应方面。这些发现表明，根据新信息更新关于这些规律的表示的能力在发育正常的婴儿和后来患有 ASD 的婴儿之间可能没有差异。
