Uenoyama K, Kanagawa R, Tamura M, Matoba M, Enomoto Y, Ohmi S
Department of Ophthalmology, Wakayama Medical College, Japan.
J Cataract Refract Surg. 1988 Mar;14(2):197-201. doi: 10.1016/s0886-3350(88)80096-8.
Among the cell components appearing on an implanted intraocular lens (IOL), the macrophage is the most active participant in the foreign-body response. The morphological stages of the macrophage in the response include not only an activated form and a flat epithelioid cell, but also a giant cell observed in the later stage of the response. The giant cells on the IOLs implanted in the rabbit eye and in the mouse peritoneal space were investigated by means of Wolter's implant cytology staining and scanning and transmission electron microscopic observation. Differences in the two biological environments as the site of IOL implantation are discussed.
在植入的人工晶状体（IOL）上出现的细胞成分中，巨噬细胞是异物反应中最活跃的参与者。巨噬细胞在反应中的形态学阶段不仅包括活化形式和平坦的上皮样细胞，还包括在反应后期观察到的巨细胞。通过沃尔特植入细胞学染色以及扫描和透射电子显微镜观察，对植入兔眼和小鼠腹腔空间的人工晶状体上的巨细胞进行了研究。讨论了作为人工晶状体植入部位的两种生物环境的差异。
