Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Hubei Key Laboratory of Animal Embryo and Molecular Breeding, Wuhan 430064, China; Key Laboratory of Prevention and Control Agents for Animal Bacteriosis of Ministry of Agriculture and Rural Affairs, Wuhan 430064, China.
Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Hubei Key Laboratory of Animal Embryo and Molecular Breeding, Wuhan 430064, China.
Poult Sci. 2021 Feb;100(2):835-843. doi: 10.1016/j.psj.2020.10.047. Epub 2020 Nov 2.
Magnolol is a multifunctional plant polyphenol. To evaluate the effects of magnolol on laying hens in the late laying period, 360 (50-week-old) laying hens were randomly assigned to 4 dietary treatments: a non-supplemented control diet (C), and control diets supplemented with 100, 200, and 300 mg/kg of magnolol (M100, M200, and M300), respectively. Each treatment had 6 replicates with 15 hens per replicate. Results showed that dietary supplementation of 200 and 300 mg/kg of magnolol increased the laying rate and the M200 group had a lower feed conversion ratio (P < 0.05). Magnolol supplementation (200 and 300 mg/kg) could linearly increase albumen height and Haugh unit of fresh eggs in the late phase of the laying cycle (P < 0.01). And magnolol linearly alleviated the decline of the albumen height and Haugh unit of eggs stored for 14 d (P < 0.01). The total superoxide dismutase activity in the ovaries of M100 group was greater than that in the other treatments (P < 0.05). As dietary magnolol levels increased, villus height of jejunum and ileum linearly increased (P < 0.01). M200 and M300 groups had higher expression level of occludin in the ileum compared with group C (P < 0.01). The level of nitric oxide production and inducible nitric oxide synthase expression in the ileum of M200 group were lower than that in the C group (P < 0.05). In conclusion, dietary supplementation of 200 and 300 mg/kg magnolol can improve hen performance, albumen quality of fresh and storage eggs, and hepatic lipid metabolism in the late laying cycle. Also, magnolol has a good effect on increasing villi and improving the intestinal mucosal mechanical barrier function.
厚朴酚是一种多功能植物多酚。为了评估厚朴酚对产蛋后期母鸡的影响，将 360 只（50 周龄）产蛋母鸡随机分为 4 种日粮处理组：未添加对照组（C）和对照组日粮分别添加 100、200 和 300mg/kg 厚朴酚（M100、M200 和 M300）。每个处理组有 6 个重复，每个重复有 15 只母鸡。结果表明，日粮中添加 200 和 300mg/kg 厚朴酚可提高产蛋率，M200 组的饲料转化率较低（P<0.05）。厚朴酚添加（200 和 300mg/kg）可线性提高产蛋后期鸡蛋的蛋白高度和哈夫单位（P<0.01）。厚朴酚线性缓解了 14d 贮存鸡蛋蛋白高度和哈夫单位的下降（P<0.01）。M100 组卵巢中超氧化物歧化酶活性大于其他处理组（P<0.05）。随着日粮中厚朴酚水平的增加，空肠和回肠的绒毛高度呈线性增加（P<0.01）。M200 和 M300 组回肠中闭合蛋白的表达水平高于 C 组（P<0.01）。M200 组回肠中一氧化氮生成和诱导型一氧化氮合酶的表达水平低于 C 组（P<0.05）。综上所述，日粮中添加 200 和 300mg/kg 厚朴酚可改善母鸡产蛋后期的生产性能、新鲜和储存鸡蛋的蛋白品质以及肝脏的脂代谢。此外，厚朴酚对增加绒毛和改善肠道黏膜机械屏障功能有很好的效果。
