脂肪源性间充质干细胞治疗僵硬性拇趾：一例报告。
Hallux rigidus treated with adipose-derived mesenchymal stem cells: A case report.
作者信息
Braile Adriano, Toro Giuseppe, De Cicco Annalisa, Cecere Antonio Benedetto, Zanchini Fabio, Schiavone Panni Alfredo
机构信息
Department of Medical and Surgical Specialties and Dentistry, University of Campania "Luigi Vanvitelli", Naples 80138, Italy.
出版信息
World J Orthop. 2021 Jan 18;12(1):51-55. doi: 10.5312/wjo.v12.i1.51.
BACKGROUND
First metatarsophalangeal joint arthritis (FMTPA), also known as hallux rigidus, is the most frequent degenerative disease of the foot. Diagnosis is made through both clinical and radiological evaluation. Regenerative medicine showed promising results in the treatment of early osteoarthritis. The aim of the present study was to report the results of a case of FMTPA treated with the injection of autologous adipose-derived mesenchymal stem cells.
CASE SUMMARY
A gentleman of 50 years of age presented with a painful hallux rigidus grade 2 resistant to any previous conservative treatment (including nonsteroidal anti-inflammatory drugs and hyaluronic acid injections). An injection of autologous adipose-derived mesenchymal stem cells into the first metatarsophalangeal joint was performed. No adverse events were reported, and both function and pain scales improved after 9 mo of follow-up.
CONCLUSION
The FMTP joint injection of mesenchymal stem cells improved symptoms and function in our patient with FMTPA at 9 mo of follow-up.
背景
第一跖趾关节关节炎（FMTPA），也称为僵硬拇趾，是足部最常见的退行性疾病。通过临床和放射学评估进行诊断。再生医学在早期骨关节炎的治疗中显示出有前景的结果。本研究的目的是报告一例经自体脂肪间充质干细胞注射治疗的FMTPA病例的结果。
病例摘要
一名50岁男性因僵硬拇趾2级疼痛前来就诊，此前任何保守治疗（包括非甾体抗炎药和透明质酸注射）均无效。对第一跖趾关节进行了自体脂肪间充质干细胞注射。未报告不良事件，随访9个月后功能和疼痛评分均有所改善。
结论
在随访9个月时，对FMTPA患者进行间充质干细胞注射到FMTP关节改善了症状和功能。
Zotero 插件