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药剂师咨询对2型糖尿病患者健康相关生活质量的影响:一项整群随机对照研究。

Impact of pharmacist counseling on health-related quality of life of patients with type 2 diabetes mellitus: a cluster randomized controlled study.

作者信息

Iskandarsyah Aulia, Puspitasari Irma M, Lestari Keri

机构信息

Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jl. Raya Bandung Sumedang KM 21, Jatinangor, West Java 45363 Indonesia.

Sekolah Tinggi Ilmu Farmasi Makassar, South Sulawesi, Indonesia.

出版信息

J Diabetes Metab Disord. 2020 Jun 3;19(2):675-682. doi: 10.1007/s40200-020-00528-x. eCollection 2020 Dec.

DOI:10.1007/s40200-020-00528-x
PMID:33520795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7843751/
Abstract

PURPOSE

The quality of life (QoL) of patients with type 2 diabetes mellitus (T2DM) is a measure of the successful outcomes of therapy. The program of management of chronic diseases "Program Pengelolaan Penyakit Kronis" (Prolanis) among patients with hypertension and T2DM is a new strategy of the Badan Penyelenggara Jaminan Sosial (BPJS), which is the Indonesian national health insurance system. Here, we analyzed the impact of pharmacist counseling interventions on health-related QoL (HRQoL) in Prolanis T2DM patients.

METHODS

This cluster randomized controlled trial was designed to include two groups [control ( = 111) and intervention ( = 109) groups], and pre- and post-test procedures. The participants were Prolanis T2DM patients who attended four primary health-care centers (Puskesmas) in Makassar City, South Sulawesi, Indonesia from August 2017 to August 2018. The intervention group received systematic counseling for 6 months. The data were collected using the Bahasa Indonesia version of the European Quality of Life 5 Dimensions 5 Levels (EQ-5D-5 L) questionnaire and were analyzed using EQ-5D preference weight for each health state with the Indonesian EQ-5D-5 L value Set. Furthermore, the EQ-5D index and the EQ-5D VAS score were calculated and HbA1c levels were assessed.

RESULTS

The change in the EQ-5D-5 L index score (post-pre) was 0.01 in the control group and 0.04 in the intervention group ( = 0.041). The change in the VAS score was -0.07in the control group (post-pre) and 2.66 in the intervention group ( = 0.000).

CONCLUSION

Pharmacist counseling may help improve the HRQoL of Prolanis T2DM patients.

摘要

目的

2型糖尿病(T2DM)患者的生活质量(QoL)是治疗成功结果的一项衡量指标。高血压和T2DM患者中的慢性病管理项目“慢性病管理项目”(Prolanis)是印度尼西亚国家医疗保险系统——社会医疗保险管理机构(BPJS)的一项新策略。在此,我们分析了药师咨询干预对Prolanis T2DM患者健康相关生活质量(HRQoL)的影响。

方法

本整群随机对照试验设计为包括两组[对照组(n = 111)和干预组(n = 109)],并采用前后测试程序。参与者为2017年8月至2018年8月期间在印度尼西亚南苏拉威西省望加锡市的四个初级卫生保健中心(Puskesmas)就诊的Prolanis T2DM患者。干预组接受了为期6个月的系统咨询。使用欧洲生活质量5维度5水平(EQ - 5D - 5L)问卷的印度尼西亚语版本收集数据,并使用印度尼西亚EQ - 5D - 5L值集对每个健康状态的EQ - 5D偏好权重进行分析。此外,计算了EQ - 5D指数和EQ - 5D视觉模拟量表(VAS)评分,并评估了糖化血红蛋白(HbA1c)水平。

结果

对照组EQ - 5D - 5L指数评分(后测 - 前测)的变化为0.01,干预组为0.04(P = 0.041)。对照组VAS评分的变化(后测 - 前测)为 - 0.07,干预组为2.66(P = 0.000)。

结论

药师咨询可能有助于改善Prolanis T2DM患者的HRQoL。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a8d/7843751/2a9e26272a11/40200_2020_528_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a8d/7843751/2a9e26272a11/40200_2020_528_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a8d/7843751/2a9e26272a11/40200_2020_528_Fig1_HTML.jpg

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