Department of Sleep Medicine, University of Miami Miller School of Medicine, Miami, Florida, USA
Department of Sleep Medicine, University of Miami Miller School of Medicine, Miami, Florida, USA.
BMJ Case Rep. 2021 Feb 1;14(2):e240496. doi: 10.1136/bcr-2020-240496.
The novel coronavirus (SARS-CoV-2) has produced millions of infections and deaths worldwide. It is believed that adaptive immunity to the virus occurs although with variation in its pattern and duration. While uncommon, confirmed reinfection with the novel coronavirus has been reported. Telemedicine has emerged as a viable tool for the delivery of healthcare in lieu of in-person patient contact. The variable and occasionally rapid course of clinical disease raises safety concerns of using telemedicine in the clinical management of acute infection with the novel coronavirus. We present a case of novel coronavirus infection in an immunocompetent individual with obstructive sleep apnea (OSA) who failed to manifest an adaptive immune response to acute infection and was subsequently reinfected. The case highlights the use of telemedicine in managing novel coronavirus respiratory disease and the potential role of OSA as a disease facilitator.
新型冠状病毒（SARS-CoV-2）已在全球范围内导致数百万人感染和死亡。据信，尽管病毒的模式和持续时间存在差异，但人体对其产生了适应性免疫。虽然罕见，但已有新型冠状病毒再次感染的确诊病例报告。远程医疗已成为替代面对面医患接触提供医疗保健的可行工具。由于临床疾病的多变性和偶尔的快速进展，人们对在新型冠状病毒急性感染的临床管理中使用远程医疗产生了安全方面的担忧。我们报告了一例免疫功能正常的阻塞性睡眠呼吸暂停（OSA）患者的新型冠状病毒感染病例，该患者未能对急性感染产生适应性免疫反应，随后又被再次感染。该病例突出了远程医疗在管理新型冠状病毒呼吸道疾病中的应用，以及 OSA 作为疾病促进因素的潜在作用。
