Department of Veterinary and Animal Sciences, Faculty of Agriculture, University of Rajshahi, Rajshahi, Bangladesh.
Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Vet Med Sci. 2021 May;7(3):820-830. doi: 10.1002/vms3.440. Epub 2021 Feb 1.
Salmonellosis in poultry is an important disease that seriously impedes the development of the poultry industry. The increased resistance to antimicrobials against Salmonella has been a major public health concern worldwide. We conducted a study from January to June 2016 in and around the Rajshahi district of Bangladesh on the commercial chicken to isolate, identify and characterize poultry-specific Salmonella, to assess the potential risk factors and to determine the antimicrobial resistance pattern of the isolates. The overall prevalence of Salmonella enterica was 41% (49/120) [95% CI: 31.95%-50.17%] with 41.7% in broiler chicken (25/60) [95% CI: 29.06%-55.12%] and 40% in layer chicken (24/60, 40%) [95% CI: 27.56%-53.46%]. Samples collected from Rajshahi city (OR = 1.37, 95% CI: 0.50-3.73) and Puthia Upazila (OR = 1.51, 95% CI: 0.56-4.12) were more likely to be positive for Salmonella than Charghat Upazila. Salmonella detection was 1.3 times higher in chicken, providing loose feed than those provided ready feed. All the isolates fermented dextrose, maltose and mannitol with the production of acid and gas, but did not ferment sucrose and lactose. The isolates showed catalase, MR, citrate utilization test and TSI agar test positive, but indole and V-P tests negative. Salmonella isolates were sensitive to ciprofloxacin (90%), gentamycin (80%), amoxicillin (75%), streptomycin (70%), ampicillin (45%) and sulfamethoxazole-trimethoprim (45%), whereas highly resistant to penicillin (100%) and nalidixic acid (100%) followed by sulfamethoxazole-trimethoprim (55%), ampicillin (40%) and amoxicillin (25%). Salmonella enterica is endemic in commercial chicken production in Bangladesh with high prevalence. A considerable proportion of Salmonella isolates was found to be resistant to the majority of the common antimicrobial drugs. A good biosecurity system could be effective for the reduction of Salmonella. It is necessary to obtain universal commitments to establish prudent antibiotic use policies.
禽沙门氏菌病是一种严重阻碍家禽业发展的重要疾病。沙门氏菌对抗微生物药物的耐药性增加已成为全球主要的公共卫生关注问题。我们于 2016 年 1 月至 6 月在孟加拉国拉杰沙希地区及周边地区对商业鸡肉进行了一项研究，旨在分离、鉴定和表征禽源沙门氏菌，评估潜在的危险因素，并确定分离株的抗菌药物耐药模式。沙门氏菌肠亚种的总流行率为 41%（49/120）[95%置信区间：31.95%-50.17%]，其中肉鸡（25/60）为 41.7%[95%置信区间：29.06%-55.12%]，蛋鸡（24/60）为 40%[95%置信区间：27.56%-53.46%]。与 Charghat 地区相比，Rajshahi 市（OR=1.37，95%置信区间：0.50-3.73）和 Puthia 地区（OR=1.51，95%置信区间：0.56-4.12）采集的样本更有可能呈沙门氏菌阳性。与提供现成饲料的鸡相比，提供松散饲料的鸡中沙门氏菌的检出率高 1.3 倍。所有分离株均发酵葡萄糖、麦芽糖和甘露醇，产生酸和气体，但不发酵蔗糖和乳糖。分离株均表现出触酶、MR、柠檬酸盐利用试验和 TSI 琼脂试验阳性，但吲哚和 V-P 试验阴性。沙门氏菌分离株对环丙沙星（90%）、庆大霉素（80%）、阿莫西林（75%）、链霉素（70%）、氨苄西林（45%）和磺胺甲恶唑-甲氧苄啶（45%）敏感，而对青霉素（100%）和萘啶酸（100%）高度耐药，其次是磺胺甲恶唑-甲氧苄啶（55%）、氨苄西林（40%）和阿莫西林（25%）。沙门氏菌肠亚种在孟加拉国商业鸡肉生产中流行，发病率很高。相当一部分沙门氏菌分离株对大多数常用抗菌药物具有耐药性。良好的生物安全系统可有效减少沙门氏菌。有必要获得普遍承诺，制定合理使用抗生素的政策。
