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50 岁及以上成年人中与 THC 相关的神经精神症状评估:系统评价和荟萃回归分析。

Evaluation of THC-Related Neuropsychiatric Symptoms Among Adults Aged 50 Years and Older: A Systematic Review and Metaregression Analysis.

机构信息

Department of Old Age Psychiatry, Institute of Psychiatry, Psychology, and Neuroscience, Division of Academic Psychiatry, King's College London, London, United Kingdom.

Department of Psychosis, Institute of Psychiatry, Psychology, and Neuroscience, Division of Academic Psychiatry, King's College London, London, United Kingdom.

出版信息

JAMA Netw Open. 2021 Feb 1;4(2):e2035913. doi: 10.1001/jamanetworkopen.2020.35913.

DOI:10.1001/jamanetworkopen.2020.35913
PMID:33528550
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7856542/
Abstract

This systematic review and metaregression analysis estimates the association between the delta-9-tetrahydrocannabinol (THC) dose of cannabinoid-based medicines and neuropsychiatric adverse events among adults aged 50 years and older.

摘要

这篇系统评价和荟萃回归分析估计了大麻素类药物中 Δ9-四氢大麻酚 (THC) 剂量与 50 岁及以上成年人神经精神不良事件之间的关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7131/7856542/11a5a542a80e/jamanetwopen-e2035913-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7131/7856542/be63505c6524/jamanetwopen-e2035913-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7131/7856542/11a5a542a80e/jamanetwopen-e2035913-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7131/7856542/be63505c6524/jamanetwopen-e2035913-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7131/7856542/11a5a542a80e/jamanetwopen-e2035913-g002.jpg

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本文引用的文献

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Lancet Psychiatry. 2019 May;6(5):427-436. doi: 10.1016/S2215-0366(19)30048-3. Epub 2019 Mar 19.
2
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Drugs. 2018 Nov;78(16):1665-1703. doi: 10.1007/s40265-018-0996-1.
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Association Between Continued Cannabis Use and Risk of Relapse in First-Episode Psychosis: A Quasi-Experimental Investigation Within an Observational Study.
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Age Ageing. 2024 Nov 1;53(11). doi: 10.1093/ageing/afae261.
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