Effects of serial administration of kainic acid on the developing brain.
作者信息
Holmes G L, Thompson J L
机构信息
Department of Neurology, Medical College of Georgia, Augusta.
出版信息
Neuropharmacology. 1988 Feb;27(2):209-12. doi: 10.1016/0028-3908(88)90172-4.
PMID:3352875
Abstract
The purpose of this study was to determine whether the repeated administration of kainic acid at 24-hr intervals results in pharmacological kindling. Rather than developing an increased intensity of seizures, this method of serial administration of kainic acid resulted in the development of tolerance to its effects.
摘要
Zotero 插件