Servicio de Alergia e Inmunología, Hospital Infantil de México Federico Gómez, Mexico City, Mexico.
Asesor Externo, Hospital Infantil de México Federico Gómez, Mexico City, Mexico.
Allergol Immunopathol (Madr). 2021 Jan 2;49(1):1-10. doi: 10.15586/aei.v49i1.35. eCollection 2021.
The Global Asthma Network (GAN) builds on the International Study of Asthma and Allergies in Childhood (ISAAC).
To compare asthma prevalence time trends in primary and secondary school children in four Mexican centers participating in ISAAC and GAN.
GAN is a cross-sectional, multicenter, epidemiological methodology carried out in groups of primary school children aged 6-7 and adolescents aged 13-14 following the ISAAC Phase Three protocol, with additional questions on risk factors and asthma management.
Overall, the prevalence of asthma symptoms and diagnosis in primary school children was higher in males than in females both in ISAAC (p < 0.05) and in GAN (p < 0.01), while adolescent females had a higher prevalence, also both in ISAAC (p < 0.001) and in GAN (p < 0.001).
The prevalence of asthma and its symptoms has increased from ISAAC Phase Three since 2003 to GAN Phase I in Mexico in 2019. These findings are in line with the increases observed in the centers with low asthma baseline prevalence in ISAAC Phase One in comparison with ISAAC Phase Three.
全球哮喘网络（GAN）建立在儿童哮喘和过敏国际研究（ISAAC）的基础上。
比较四个参与 ISAAC 和 GAN 的墨西哥中心的小学生和中学生哮喘患病率的时间趋势。
GAN 是一项横断面、多中心的流行病学方法，按照 ISAAC 第三阶段方案，对 6-7 岁的小学生和 13-14 岁的青少年进行分组，同时还增加了有关危险因素和哮喘管理的问题。
总体而言，在 ISAAC（p<0.05）和 GAN（p<0.01）中，小学生的哮喘症状和诊断患病率男性均高于女性，而青少年女性的患病率也更高，在 ISAAC（p<0.001）和 GAN（p<0.001）中均如此。
自 2003 年 ISAAC 第三阶段以来，墨西哥 GAN 第一阶段的哮喘和哮喘症状的患病率有所增加。这些发现与在 ISAAC 第一阶段基线哮喘患病率较低的中心与 ISAAC 第三阶段相比观察到的增加一致。
