美国农村和尼日利亚农村黑人人口中帕金森病患病率的比较：挨家挨户的社区研究。

Comparison of the prevalence of Parkinson's disease in black populations in the rural United States and in rural Nigeria: door-to-door community studies.

作者信息

Schoenberg B S, Osuntokun B O, Adeuja A O, Bademosi O, Nottidge V, Anderson D W, Haerer A F

机构信息

Neuroepidemiology Branch, National Institute of Neurological and Communicative Disorders and Stroke, Bethesda, MD 20892.

出版信息

Neurology. 1988 Apr;38(4):645-6. doi: 10.1212/wnl.38.4.645.

DOI:10.1212/wnl.38.4.645

PMID:3352927

Abstract

A door-to-door survey of Parkinson's disease (PD) in Copiah County, Mississippi, using a pretested screening procedure (with a high sensitivity for detecting PD), followed by examination of all positives by a senior neurologist, revealed similar prevalence ratios for blacks and whites. The same procedure was applied in the community of Igbo-Ora, Nigeria, a black population of West Africa. To assure uniformity in the procedures and application of the diagnostic criteria, a neurologist from each survey site visited the other site. Among a black population of 3,521 over age 39 in Copiah County, there were 12 cases of PD, with an age-adjusted prevalence ratio of 341/100,000. The comparable figures for Igbo-Ora were as follows: population over age 39 = 3,412; cases of PD = 2; age-adjusted prevalence ratio = 67/100,000.

摘要

在密西西比州科皮亚县，采用预先测试过的筛查程序（对检测帕金森病具有高灵敏度）对帕金森病（PD）进行挨家挨户调查，随后由一位资深神经科医生对所有阳性病例进行检查，结果显示黑人和白人的患病率相似。在西非的黑人聚居区尼日利亚的伊博奥拉社区也采用了相同的程序。为确保程序和诊断标准应用的一致性，每个调查地点的一名神经科医生访问了另一个地点。在科皮亚县39岁以上的3521名黑人中，有12例帕金森病病例，年龄调整后的患病率为341/100,000。伊博奥拉的可比数据如下：39岁以上人口 = 3412；帕金森病病例 = 2；年龄调整后的患病率 = 67/100,000。