14105Kuwait Oil Company, Kuwait.
Faculty of Medicine, 37603Kuwait University, Kuwait.
Nutr Health. 2021 Jun;27(2):181-189. doi: 10.1177/0260106020981819. Epub 2021 Feb 2.
Functional food ingredients, such as dietary fiber, long-chain polyunsaturated fatty acids, and high-quality protein, have been shown to help control blood glucose concentration and lower high blood pressure (BP), as well as improving other cardiovascular disease risk factors. However, little research has assessed the impacts of consuming chia seeds, which are rich in these nutrients, on metabolic and physiological outcomes, and results are conflicting.
The study aimed to investigate the possible effects of chia seeds on fasting blood glucose, insulin, glycated hemoglobin, BP, lipid profile, body weight, and the inflammatory marker - high-sensitivity C-reactive protein - in people with type 2 diabetes (T2DM).
Adults with T2DM ( = 42) were randomly assigned equally to the chia seed group, which consumed 40 g/day chia seeds for 12 weeks, or a control group, which did not consume any supplement. Blood samples were collected at baseline and after a 12-week intervention period to assess the study outcomes, such as glycemic control, BP, cardiovascular risk parameters including lipid profile, inflammatory marker, and body weight.
Adjusted for gender and baseline values, the chia seed group had systolic BP (SBP) significantly reduced compared to control [ (1) = 2.867, = 0.007, = 0.174]. No differences were observed in any other parameter tested in the chia seed or control group.
People with T2DM and hypertension, maintaining usual dietary consumption, physical activity pattern, and medications, had significantly reduced SBP compared to the control group when having consumed 40 g/d of chia seeds for 12 weeks.
膳食纤维、长链多不饱和脂肪酸和优质蛋白质等功能性食品成分已被证明有助于控制血糖浓度和降低高血压（BP），并改善其他心血管疾病风险因素。然而，很少有研究评估食用富含这些营养成分的奇亚籽对代谢和生理结果的影响，且结果相互矛盾。
本研究旨在调查奇亚籽对 2 型糖尿病（T2DM）患者空腹血糖、胰岛素、糖化血红蛋白、BP、血脂谱、体重和炎症标志物——高敏 C 反应蛋白的可能影响。
将 42 名 T2DM 成人随机均等分为奇亚籽组和对照组，奇亚籽组每天食用 40 g 奇亚籽，持续 12 周，对照组不食用任何补充剂。在基线和 12 周干预期后采集血样，以评估研究结果，如血糖控制、BP、包括血脂谱、炎症标志物和体重在内的心血管风险参数。
校正性别和基线值后，与对照组相比，奇亚籽组的收缩压（SBP）显著降低[（1）= 2.867，= 0.007，= 0.174]。奇亚籽组和对照组在其他任何测试参数上均未观察到差异。
在保持常规饮食摄入、身体活动模式和药物治疗的情况下，T2DM 和高血压患者每天食用 40 g 奇亚籽 12 周后，与对照组相比，SBP 显著降低。
