AlMulhim Johara, AlRasheed Mohannad Rasheed
College of Medicine, King Faisal University, 4008, Hofuf, Ahsa, Saudi Arabia.
Department of Medical Imaging, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
Radiol Case Rep. 2021 Jan 22;16(3):744-747. doi: 10.1016/j.radcr.2020.09.048. eCollection 2021 Mar.
Herlyn-Werner-Wunderlich syndrome, is a rare urogenital congenital anomaly. Coexisting Mullerian ducts anomalies and ovarian neoplasms are rarely reported. We present the first case of Herlyn-Werner-Wunderlich syndrome with borderline serous neoplasm of the ovary. A 29-year-old married female with primary infertility and elevated level of cancer antigen 125 (CA-125), underwent pelvic magnetic resonance imaging for evaluation which revealed uterus didelphys, obstructed right hemivagina, right renal agenesis as well as right ovarian cystic lesion. Ovary preserving laparoscopic cystectomy was performed with a pathological diagnosis of a serous borderline tumor. Although rarely reported, Mullerian ducts anomalies and uterine or ovarian remnant neoplasms can occur. These few case reports may suggest an underlying, yet to be discovered, genetic association of Mullerian ducts anomalies and development of ovarian neoplasms of various pathological subtypes.
赫林-韦纳-温德利希综合征是一种罕见的泌尿生殖系统先天性异常。并存的苗勒管异常和卵巢肿瘤鲜有报道。我们报告首例患有卵巢交界性浆液性肿瘤的赫林-韦纳-温德利希综合征病例。一名29岁已婚女性，原发性不孕且癌抗原125（CA-125）水平升高，接受盆腔磁共振成像评估，结果显示双子宫、右侧阴道梗阻、右肾缺如以及右侧卵巢囊性病变。实施了保留卵巢的腹腔镜囊肿切除术，病理诊断为浆液性交界性肿瘤。尽管鲜有报道，但苗勒管异常与子宫或卵巢残留肿瘤可能会发生。这少数病例报告可能提示苗勒管异常与各种病理亚型卵巢肿瘤发生之间存在潜在的、尚未被发现的遗传关联。
