From the Department of Pediatrics and Neonatology, Hospital Universitario de Guadalajara, Guadalajara, Spain.
Division of Neonatology, Insituto del Niño y del Adolescente, Hospital Clinico San Carlos-IdISSC.
Pediatr Infect Dis J. 2021 Jun 1;40(6):e230-e233. doi: 10.1097/INF.0000000000003080.
Congenital cutaneous candidiasis is an infrequent invasive fungal infection that usually appears in the first days of life. Extremely low birth weight infants are the most frequently affected. Classic presentation includes diffuse extensive erythematous rash with papules, plaques, pustules and vesicles, which later undergoes desquamation. Systemic dissemination is common in extremely low birth weight infants. Blood, urine and cerebrospinal fluid evaluation should be included in the initial assessment. Early and prolonged treatment has been associated with decreased mortality. We report the case of congenital cutaneous candidiasis in a preterm infant. Early skin lesion recognition allowed establishing adequate treatment in the first hours of life.
先天性皮肤念珠菌病是一种罕见的侵袭性真菌感染，通常在出生后的头几天出现。极低出生体重儿是最常受影响的人群。典型表现包括弥漫性广泛红斑性丘疹、斑块、脓疱和水疱，随后出现脱皮。极低出生体重儿常发生全身播散。在初始评估中应包括血液、尿液和脑脊液评估。早期和长期治疗与降低死亡率相关。我们报告了一例早产儿先天性皮肤念珠菌病病例。早期识别皮肤病变使得在生命的最初几小时内就能进行适当的治疗。
