Seale Emily, Spurr Alison, Teo Iris, Glassman Steven J
Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Division of Dermatology, Faculty of Medicine, The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.
SAGE Open Med Case Rep. 2023 Mar 28;11:2050313X231160949. doi: 10.1177/2050313X231160949. eCollection 2023.
Disseminated cutaneous candidiasis is a rare manifestation of candidiasis that arises most commonly from . It is described as a widespread erythematous papulopustular skin infection that typically affects premature newborns or immunocompromised patients. While candidal infections usually respond well to antifungal therapy, the clinical presentation of disseminated cutaneous candidiasis can often mimic a variety of other dermatologic conditions, that can lead to delayed diagnosis and treatment. We present a 67-year-old comorbid male patient with widespread erythema and superficial pustules resembling acute generalized exanthematous pustulosis (AGEP) that was actually an unexpected manifestation of disseminated cutaneous candidiasis. Prompt initiation of a topical and oral antifungal regimen contributed to marked improvement. Given the high frequency of drug eruptions in comorbid patients receiving multiple medications, alternate diagnoses like infections should be included in the differential diagnosis.
播散性皮肤念珠菌病是念珠菌病的一种罕见表现形式，最常见于……它被描述为一种广泛的红斑丘疹脓疱性皮肤感染，通常影响早产儿或免疫功能低下的患者。虽然念珠菌感染通常对抗真菌治疗反应良好，但播散性皮肤念珠菌病的临床表现常常可模仿多种其他皮肤病，这可能导致诊断和治疗延迟。我们报告一例67岁男性合并症患者，其广泛的红斑和浅表脓疱类似急性泛发性脓疱性皮病（AGEP），而实际上是播散性皮肤念珠菌病的意外表现。及时开始局部和口服抗真菌治疗方案促使病情显著改善。鉴于接受多种药物治疗的合并症患者中药物疹的发生率较高，鉴别诊断中应包括感染等其他诊断。
