香烟烟雾吸入模式与支气管反应性。
Cigarette smoke inhalation patterns and bronchial reactivity.
作者信息
Taylor D R, Reid W D, Paré P D, Fleetham J A
机构信息
Department of Medicine, University of British Columbia, Vancouver, Canada.
出版信息
Thorax. 1988 Jan;43(1):65-70. doi: 10.1136/thx.43.1.65.
Abstract
The manner in which a cigarette is smoked varies considerably between individuals and may be an important determinant of the altered bronchial reactivity observed in cigarette smokers. Twenty smokers were examined to determine the relationship between cigarette smoke inhalation patterns and bronchial reactivity. Inhalation patterns were measured non-invasively with a respiratory inductive plethysmograph and these were related to the provocative concentration of histamine that caused a 20% fall in FEV1 (PC20) and to the cough threshold for inhaled citric acid. Histamine PC20 values were inversely correlated with depth and rate of inhalation. Cough threshold was inversely correlated with greater cigarette consumption and with depth of inhalation.
摘要
不同个体吸烟的方式差异很大，这可能是导致吸烟者支气管反应性改变的一个重要决定因素。对20名吸烟者进行了检查，以确定香烟烟雾吸入模式与支气管反应性之间的关系。使用呼吸感应体积描记器以非侵入性方式测量吸入模式，并将其与导致第一秒用力呼气量（FEV1）降低20%的组胺激发浓度（PC20）以及吸入柠檬酸的咳嗽阈值相关联。组胺PC20值与吸入深度和速率呈负相关。咳嗽阈值与更大的香烟消费量以及吸入深度呈负相关。
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