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经口内镜甲状腺手术颏下入路(TOETVA)与内镜甲状腺手术腋窝入路(ETABA)在甲状腺手术中的疗效和生活质量比较:非随机临床试验。

A comparison of efficacy and quality of life between transoral endoscopic thyroidectomy vestibular approach (TOETVA) and endoscopic thyroidectomy axillo-breast approach (ETABA) in thyroid surgery: non-randomized clinical trial.

机构信息

Department of Otolaryngology, Faculty of Medicine, Srinakharinwirot University, 62 Moo 7, Rangsit-Nakhon Nayok Road, Ongkharak, Nakhon Nayok, 26120, Thailand.

出版信息

Eur Arch Otorhinolaryngol. 2021 Oct;278(10):4043-4049. doi: 10.1007/s00405-021-06639-2. Epub 2021 Feb 4.

Abstract

PURPOSE

Recently, there are many new surgical methods of endoscopic thyroidectomy, which have advantages in cosmetic results while do not increase the complication rates. This study was conducted to evaluate and compare both intra- and post-operative results and quality of life between TOETVA and endoscopic thyroidectomy axillo-breast approach (ETABA).

MATERIALS AND METHODS

A non-randomized, patient preference clinical trial was performed in Otorhinolaryngology, Head and Neck surgery department, HRH Princess Maha Chakri Sirindhorn Medical center. Patients who decided to go for endoscopic thyroidectomy were allocated into two groups. Demographics data, operative time, intra-operative blood loss, post-operative pain score, length of hospital stay, complications were collected. Overall satisfaction was evaluated by visual analogue scale and quality of life was evaluated by SF-36 questionnaires.

RESULTS

22 patients were totally included and equally allocated in 2 groups (11 patients per group). All of the operations were lobectomy. There was no significant difference in demographic data. The results showed that pain score at 3 days post-operation and average pain score were significantly higher in TOETVA group. Average pain score was 3.67 ± 1.11 in ETABA group and 5.15 ± 1.35 in TOETVA (p = 0.011); however, the operative time, intra-operative blood loss, length of hospital stay, complications and overall satisfaction were not significantly different. Different change in the quality of life was not detected in both groups.

CONCLUSION

Transoral endoscopic thyroidectomy vestibular approach and ETABA both have comparable results and do not worsen the quality of life.

摘要

目的

目前有多种新的内镜甲状腺手术方法,这些方法在美容效果方面具有优势,同时并不增加并发症发生率。本研究旨在评估和比较经口内镜甲状腺腔镜手术前庭入路(TOETVA)与内镜甲状腺腋窝入路(ETABA)的围手术期结果和生活质量。

材料和方法

本非随机、患者偏好的临床试验在耳鼻喉头颈外科 HRH 玛哈扎克里·诗琳通公主医学中心进行。决定行内镜甲状腺切除术的患者被分配至两组。收集人口统计学数据、手术时间、术中出血量、术后疼痛评分、住院时间、并发症等数据。通过视觉模拟评分评估总体满意度,通过 SF-36 问卷评估生活质量。

结果

共纳入 22 例患者,平均分为 2 组(每组 11 例)。所有手术均为腺叶切除术。两组患者的人口统计学数据无显著差异。结果显示,TOETVA 组术后 3 天的疼痛评分和平均疼痛评分显著更高。ETABA 组平均疼痛评分为 3.67±1.11,TOETVA 组为 5.15±1.35(p=0.011);然而,手术时间、术中出血量、住院时间、并发症和总体满意度无显著差异。两组的生活质量均未发生明显变化。

结论

经口内镜甲状腺腔镜手术前庭入路与 ETABA 具有相似的结果,且不会降低生活质量。

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