Department of Food Science, School of Food Engineering, University of Campinas, Campinas, SP, 13083-862, Brazil.
Brazilian Agricultural Research Corporation, Embrapa Environment, Jaguariúna, SP, 13820-000, Brazil.
Chemosphere. 2021 Jul;274:129753. doi: 10.1016/j.chemosphere.2021.129753. Epub 2021 Jan 22.
Acremonium camptosporum, a fungus associated with the marine sponge Aplysina fulva, was collected from the isolated mid-Atlantic Saint Peter and Saint Paul Archipelago, Brazil, and was found to produce secondary metabolites that displayed antibacterial activities. Mass spectra data obtained by UPLC-ESI-MS/MS analyses of these extracts were compared to several databases and revealed the presence of several different cytotoxic acremonidins and acremoxanthones. The close association between the sponge and the fungi with its compounds could be of strategic importance in defending both from the high predation pressure and spatial competition in the warm-water scarps of the islands.
从巴西孤立的中大西洋圣彼得和圣保罗群岛采集到与海洋海绵 Aplysina fulva 相关的真菌 Acremonium camptosporum，并发现其产生的次生代谢产物具有抗菌活性。通过 UPLC-ESI-MS/MS 分析这些提取物获得的质谱数据与几个数据库进行了比较，结果表明存在几种不同的细胞毒性 acremonidins 和 acremoxanthones。海绵与真菌及其化合物之间的密切联系，对于保护它们免受岛屿温暖水崖中高捕食压力和空间竞争的影响可能具有战略重要性。
