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COVID-19 相关焦虑会加重耳鸣。

COVID-19 associated anxiety enhances tinnitus.

机构信息

Department of Otolaryngology-Head and Neck Surgery, Mianyang Central Hospital, Mianyang, Sichuan, China.

Department of Otolaryngology-Head and Neck Surgery, Sichuan Provincial People's Hospital and Sichuan Academy of Medical Sciences, Chengdu, Sichuan, China.

出版信息

PLoS One. 2021 Feb 5;16(2):e0246328. doi: 10.1371/journal.pone.0246328. eCollection 2021.

Abstract

To investigate if the anxiety associated with coronavirus disease 2019 (COVID-19) is a promoting factor to tinnitus. A retrospective research design collected from 188 tinnitus patients, was used to compare the clinical characteristics of tinnitus between the patients in 2020 under pandemic pressure and those from the matching period in 2019. While anxiety was quantified using the Zung's Self-rating Anxiety Scale (SAS), tinnitus severity was evaluated using the Tinnitus Handicap Inventory (THI) questionnaire and the test of tinnitus loudness (TL). The assessments were repeated after the sound therapy plus educational counselling (STEC) for 38 patients in 2020 and 58 patients in 2019 and compared with EC alone therapy for 42 patients in 2020 and 17 patients in 2019. A large increase in anxiety was evident in 2020 in both case rate and SAS. The treatment of both methods was less effective in 2020. SAS, THI and TL were all deteriorated after the EC alone treatment in 2020, while an improvement was seen in 2019. This suggests that EC alone could not counteract the stress by COVID-19 at all, and the stress, if not managed well, can significantly increase the severity of tinnitus and associated anxiety. By using the EC subgroup in virtual control, we conclude that anxiety can serve as a promoting factor to tinnitus. We believe that this is the first study report that confirm the causative/promotive role of anxiety on tinnitus during COVID-19 pandemic.

摘要

目的

探讨新型冠状病毒肺炎(COVID-19)相关焦虑是否是导致耳鸣的一个促进因素。方法:采用回顾性研究设计,收集了 188 例耳鸣患者的资料,比较了在 COVID-19 大流行压力下的 2020 年患者与 2019 年同期患者的耳鸣临床特征。采用zung 焦虑自评量表(SAS)量化焦虑,采用耳鸣残疾量表(THI)问卷和耳鸣响度测试(TL)评估耳鸣严重程度。对 2020 年的 38 例患者和 2019 年的 58 例患者进行了声音治疗加教育咨询(STEC)后的评估,并与 2020 年的 42 例患者和 2019 年的 17 例患者单独进行了 EC 治疗后的评估进行了比较。结果:2020 年,无论是病例发生率还是 SAS,焦虑都明显增加。两种方法的治疗效果在 2020 年都有所下降。在 2020 年单独进行 EC 治疗后,SAS、THI 和 TL 均恶化,而在 2019 年则有所改善。这表明 EC 单独治疗根本无法抵消 COVID-19 带来的压力,如果压力得不到很好的管理,耳鸣的严重程度及其相关的焦虑会显著增加。通过使用虚拟对照的 EC 亚组,我们得出结论,焦虑可能是耳鸣的一个促进因素。我们相信,这是首次报道 COVID-19 大流行期间焦虑对耳鸣有因果关系或促进作用的研究报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32e9/7864409/2d1a69eec4e2/pone.0246328.g001.jpg

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