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新冠病毒感染后患者耳鸣的患病率和预后:一项横断面调查。

Prevalence and prognosis of tinnitus in post-COVID-19 patients: a cross-sectional survey.

机构信息

NHC Key Laboratory of Hearing Medicine (Fudan University), Demin Han's Academician Workstation, Eye & ENT Hospital, Otolaryngology Research Institute, Shanghai, PR China.

Clinical Research Unit of Eye & ENT Hospital, Fudan University, Shanghai, PR China.

出版信息

Epidemiol Infect. 2024 Nov 8;152:e137. doi: 10.1017/S095026882400147X.

Abstract

Recent developments have indicated a potential association between tinnitus and COVID-19. The study aimed to understand tinnitus following COVID-19 by examining its severity, recovery prospects, and connection to other lasting COVID-19 effects. Involving 1331 former COVID-19 patients, the online survey assessed tinnitus severity, cognitive issues, and medical background. Of the participants, 27.9% reported tinnitus after infection. Findings showed that as tinnitus severity increased, the chances of natural recovery fell, with more individuals experiencing ongoing symptoms ( 0.001). Those with the Grade II mild tinnitus (OR = 3.68; CI = 1.89-7.32;  = 0.002), Grade III tinnitus (OR = 3.70; CI = 1.94-7.22;  < 0.001), Grade IV (OR = 6.83; CI = 3.73-12.91;  < 0.001), and a history of tinnitus (OR = 1.96; CI = 1.08-3.64;  = 0.03) had poorer recovery outcomes. Grade IV cases were most common (33.2%), and severe tinnitus was strongly associated with the risk of developing long-term hearing loss, anxiety, and emotional disorders ( < 0.001). The study concludes that severe post-COVID tinnitus correlates with a worse prognosis and potential hearing loss, suggesting the need for attentive treatment and management of severe cases.

摘要

最近的发展表明耳鸣与 COVID-19 之间存在潜在关联。本研究旨在通过检查 COVID-19 后耳鸣的严重程度、恢复前景及其与其他持续 COVID-19 影响的关系,来了解 COVID-19 后的耳鸣。该研究纳入了 1331 名曾感染过 COVID-19 的患者,通过在线调查评估了他们的耳鸣严重程度、认知问题和医疗背景。在参与者中,27.9%的人在感染后报告有耳鸣。研究结果表明,随着耳鸣严重程度的增加,自然恢复的机会减少,更多的人出现持续症状(0.001)。那些患有二级轻度耳鸣(OR=3.68;CI=1.89-7.32;=0.002)、三级耳鸣(OR=3.70;CI=1.94-7.22;<0.001)、四级耳鸣(OR=6.83;CI=3.73-12.91;<0.001)和有耳鸣病史(OR=1.96;CI=1.08-3.64;=0.03)的患者恢复效果较差。四级病例最为常见(33.2%),严重耳鸣与长期听力损失、焦虑和情绪障碍的风险密切相关(<0.001)。研究得出结论,COVID-19 后严重的耳鸣与预后较差和潜在听力损失相关,这表明需要对严重病例进行积极治疗和管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1948/11574603/07111abc311b/S095026882400147X_fig1.jpg

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