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本文引用的文献

1
Picosecond Time Resolution with Avalanche Amorphous Selenium.采用雪崩非晶硒的皮秒时间分辨率
ACS Photonics. 2019 Jun 19;6(6):1338-1344. doi: 10.1021/acsphotonics.9b00012. Epub 2019 Mar 26.
2
On light sharing TOF-PET modules with depth of interaction and 157 ps FWHM coincidence time resolution.在具有交互作用深度和 157 ps FWHM 符合时间分辨率的光分享 TOF-PET 模块上。
Phys Med Biol. 2019 Aug 7;64(15):155008. doi: 10.1088/1361-6560/ab2cb0.
3
Evaluation of a clinical TOF-PET detector design that achieves ⩽100 ps coincidence time resolution.评估一种临床 TOF-PET 探测器设计,该设计可实现 ⩽100 ps 的符合时间分辨率。
Phys Med Biol. 2018 Jun 7;63(11):115011. doi: 10.1088/1361-6560/aac504.
4
Comparative study of afterpulsing behavior and models in single photon counting avalanche photo diode detectors.单光子计数雪崩光电二极管探测器中后脉冲行为及模型的对比研究
Sci Rep. 2018 Mar 22;8(1):5076. doi: 10.1038/s41598-018-23398-z.
5
Toward Scintillator High-Gain Avalanche Rushing Photoconductor Active Matrix Flat Panel Imager (SHARP-AMFPI): Initial fabrication and characterization.面向闪烁体高增益雪崩流光光电导型有源矩阵平板成像器 (SHARP-AMFPI):初步制作和特性研究。
Med Phys. 2018 Feb;45(2):794-802. doi: 10.1002/mp.12693. Epub 2017 Dec 18.
6
Silicon single-photon avalanche diodes with nano-structured light trapping.具有纳米结构光捕获的硅单光子雪崩二极管。
Nat Commun. 2017 Sep 20;8(1):628. doi: 10.1038/s41467-017-00733-y.
7
Advances in coincidence time resolution for PET.正电子发射断层扫描(PET)符合时间分辨率的进展
Phys Med Biol. 2016 Mar 21;61(6):2255-64. doi: 10.1088/0031-9155/61/6/2255. Epub 2016 Feb 25.
8
Advances in time-of-flight PET.飞行时间正电子发射断层扫描技术的进展
Phys Med. 2016 Jan;32(1):12-22. doi: 10.1016/j.ejmp.2015.12.007. Epub 2016 Jan 6.
9
Analytical calculation of the lower bound on timing resolution for PET scintillation detectors comprising high-aspect-ratio crystal elements.包含高纵横比晶体元件的正电子发射断层扫描(PET)闪烁探测器时间分辨率下限的解析计算。
Phys Med Biol. 2015 Jul 7;60(13):5141-61. doi: 10.1088/0031-9155/60/13/5141. Epub 2015 Jun 17.
10
Sub-100 ps coincidence time resolution for positron emission tomography with LSO:Ce codoped with Ca.采用钙共掺杂的LSO:Ce进行正电子发射断层扫描时低于100皮秒的符合时间分辨率。
Phys Med Biol. 2015 Jun 21;60(12):4635-49. doi: 10.1088/0031-9155/60/12/4635. Epub 2015 May 28.

用于 TOF-PET 的纳米图案多井雪崩硒探测器。

Nanopattern multi-well avalanche selenium detector for TOF-PET.

机构信息

Department of Radiology, Stony Brook University, Stony Brook, NY, United States of America.

出版信息

Phys Med Biol. 2021 Jun 30;66(13). doi: 10.1088/1361-6560/abe3d0.

DOI:10.1088/1361-6560/abe3d0
PMID:33545696
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11025682/
Abstract

For the first time, we propose using amorphous selenium (-Se) as the photoconductive material for time-of-flight (TOF) detectors. Advantages of avalanche-mode-Se are having high fill factor, low excess noise due to unipolar photoconductive gain, band transport in extended states with the highest possible mobility, and negligible trapping. The major drawback of-Se is its poor single-photon time resolution and low carrier mobility due to shallow-traps, problems that must be circumvented for TOF applications. We propose a nanopattern multi-well-Se detector (MWSD) to enable both impact ionization avalanche gain and unipolar time-differential (UTD) charge sensing in one device. Our experimental results show that UTD charge sensing in avalanche-mode-Se improves time-resolution by nearly 4 orders-of-magnitude. In addition, we used Cramér-Rao lower bound analysis and Monte Carlo simulations to demonstrate the viability of our MWSD for low statistics photon imaging modalities such as PET despite it being a linear-mode device. Based on our results, our device may achieve 100 ps coincidence time resolution in TOF PET with a material that is low cost and uniformly scalable to large area.

摘要

我们首次提出使用非晶硒 (-Se) 作为飞行时间 (TOF) 探测器的光电导材料。雪崩模式-Se 的优点包括具有高填充因子、由于单极光电导增益导致的低过剩噪声、扩展态中的能带输运和可能的最高迁移率,以及可忽略的俘获。-Se 的主要缺点是由于浅陷阱导致的单光子时间分辨率差和载流子迁移率低,这些问题必须在 TOF 应用中加以解决。我们提出了一种纳米图案多阱硒探测器 (MWSD),以使单粒子雪崩增益和单极时间差分 (UTD) 电荷感应在一个器件中同时实现。我们的实验结果表明,雪崩模式-Se 中的 UTD 电荷感应将时间分辨率提高了近 4 个数量级。此外,我们使用克拉美罗下限分析和蒙特卡罗模拟来证明我们的 MWSD 对于低统计光子成像模式(如 PET)的可行性,尽管它是一种线性模式器件。基于我们的结果,我们的设备可能在具有低成本和均匀可扩展到大面积的材料的 TOF PET 中实现 100 ps 符合时间分辨率。