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高血压管理的当前挑战:从更好的高血压诊断到提高患者的依从性和血压控制。

Current challenges for hypertension management: From better hypertension diagnosis to improved patients' adherence and blood pressure control.

机构信息

Istituto Auxologico Italiano, IRCCS, Department of Cardiovascular, Neural and Metabolic Sciences, S.Luca Hospital, Milan, Italy; Department of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy.

Istituto Auxologico Italiano, IRCCS, Department of Cardiovascular, Neural and Metabolic Sciences, S.Luca Hospital, Milan, Italy; Department of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy.

出版信息

Int J Cardiol. 2021 May 15;331:262-269. doi: 10.1016/j.ijcard.2021.01.070. Epub 2021 Feb 4.

DOI:10.1016/j.ijcard.2021.01.070
PMID:33548384
Abstract

Hypertension control still remains a largely unmet challenge for public health systems. Despite the progress in blood pressure (BP) measurement techniques, and the availability of effective and safe antihypertensive drugs, a large number of hypertensive patients are not properly identified, and a significant proportion of those who receive antihypertensive treatment fail to achieve satisfactory control of their BP levels. It is thus not surprising that hypertension is still a major contributor to disease burden and disability worlwide, even in developed countries. This paper will address current challenges in hypertension management and potential strategies for an improvement in this field. In its first part relevant issues related to hypertension diagnosis will be addressed, in particular how to improve identification of sustained BP elevation and specific BP phenotypes such as white coat and masked hypertension trough the combined use of office and out-of-office BP monitoring techniques. In its second part focus will be on how to improve achievement of hypertension control in treated patients by optimization and simplification of medication regimens, including more efficient selection and titration of antihypertensive drugs and their combinations, aimed at achieving a more consistent 24hBP control; and by favoring a more active patients' and physicians' involvement in hypertension management also through BP telemonitoring and mobile health technologies.

摘要

高血压控制仍然是公共卫生系统面临的一大挑战。尽管血压(BP)测量技术取得了进展,并且有有效的、安全的降压药物,但仍有大量高血压患者未得到正确识别,而且相当一部分接受降压治疗的患者未能达到满意的血压控制水平。因此,高血压仍然是全世界疾病负担和残疾的主要原因,即使在发达国家也是如此。本文将探讨高血压管理中的当前挑战和改善这一领域的潜在策略。在第一部分中,将讨论与高血压诊断相关的问题,特别是如何通过联合使用诊室和诊室外血压监测技术,改善对持续性血压升高和特定血压表型(如白大衣高血压和隐匿性高血压)的识别。在第二部分中,将重点讨论如何通过优化和简化药物治疗方案,包括更有效地选择和滴定降压药物及其组合,以实现更一致的 24 小时血压控制,从而改善治疗患者的高血压控制率;并通过促进患者和医生更积极地参与高血压管理,包括通过血压远程监测和移动健康技术,来实现这一目标。

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