Hülsemann J, Kordass U, Sander G, Schmidt E, Schöch G
Forschungsinstitut für Kinderenährung, Dortmund, FRG.
Ann Nutr Metab. 1988;32(1):44-51. doi: 10.1159/000177391.
Single urine voidings were collected twice a week in the clinical course of 12 low-birth-weight infants (gestational age: 31.8 +/- 2.8 weeks; birth weight: 1,383 +/- 308 g) and analyzed for 3-methylhistidine and creatinine. The mean 3-methylhistidine/creatinine ratio for 6 healthy, well-fed, growing low-birth-weight infants was 20.2 +/- 1.9 mumol/mmol. In the clinical course of single individuals a rise of urinary 3-methylhistidine/creatinine ratio was observed in cases of acute infection and/or low energy supply (less than 100 kcal/kg/day) frequently coupled with insufficient weight gain. Mean 3-methylhistidine/creatinine ratios in infants with hyaline membrane syndrome under artificial respiration were generally higher than in the controls matched for energy supply.
在12名低体重婴儿（胎龄：31.8±2.8周；出生体重：1383±308克）的临床过程中，每周收集两次单次排尿，并分析其中的3-甲基组氨酸和肌酐。6名健康、营养良好、正在成长的低体重婴儿的平均3-甲基组氨酸/肌酐比值为20.2±1.9μmol/mmol。在个体的临床过程中，观察到在急性感染和/或能量供应不足（低于100千卡/千克/天）且常伴有体重增加不足的情况下，尿3-甲基组氨酸/肌酐比值会升高。接受人工呼吸的透明膜病综合征婴儿的平均3-甲基组氨酸/肌酐比值通常高于能量供应匹配的对照组。
