支气管源性癌的外科治疗：720例开胸手术的回顾性研究

Surgical treatment of bronchogenic carcinoma: a retrospective study of 720 thoracotomies.

作者信息

Deneffe G, Lacquet L M, Verbeken E, Vermaut G

机构信息

Department of Thoracic Surgery, U.Z. Pellenberg, University of Leuven, Belgium.

出版信息

Ann Thorac Surg. 1988 Apr;45(4):380-3. doi: 10.1016/s0003-4975(98)90009-1.

DOI:10.1016/s0003-4975(98)90009-1

PMID:3355279

Abstract

Seven hundred and twenty patients with primary bronchogenic carcinoma were operated on at the Pellenberg Clinic, K.U. Leuven, Belgium, between January 1, 1970, and January 1, 1985. Almost 45% of the resections were pneumonectomies and 47% were lobectomies. Mortality was 6.9% and 2.9%, respectively. Patients with squamous cell carcinoma (Stages I and II) who underwent lobectomy or pneumonectomy had an absolute 5-year survival rate of 52.8% (93/176); it was 21% (4/19) in the T3 N0/N1 subgroup. Patients with adenocarcinoma who underwent a lobectomy had a 5-year survival rate of 49% (26/53) in the T1/T2 N0 group and of 27% (3/11) in the T1/T2 N1 group. Only 13.6% (3/22) of patients survived 5 years if a pneumonectomy had to be performed. Only 1 in 22 N2 patients survived 5 years after resection.

摘要

1970年1月1日至1985年1月1日期间，比利时鲁汶大学佩伦贝格诊所对720例原发性支气管癌患者进行了手术。几乎45%的切除术为全肺切除术，47%为肺叶切除术。死亡率分别为6.9%和2.9%。接受肺叶切除术或全肺切除术的鳞状细胞癌（Ⅰ期和Ⅱ期）患者的5年绝对生存率为52.8%（93/176）；在T3 N0/N1亚组中为21%（4/19）。接受肺叶切除术的腺癌患者在T1/T2 N0组中的5年生存率为49%（26/53），在T1/T2 N1组中为27%（3/11）。如果必须进行全肺切除术，只有13.6%（3/22）的患者存活5年。在N2患者中，每22例只有1例在切除术后存活5年。