Sinclair J D, Tiihonen K
Research Laboratory, Finnish Alcohol Company, Alko Ltd., Helsinki.
Alcohol. 1988 Jan-Feb;5(1):85-7. doi: 10.1016/0741-8329(88)90048-1.
Rats that have had at least several weeks of access to ethanol generally react to a week or more without it by drinking more alcohol on the first few days of renewed access. This alcohol-deprivation effect was again seen now in 25 male Long-Evans rats but not in 21 males of the heavy-drinking AA line. The present results obtained with F51 generation AAs differ from ones obtained previously with F32 AAs, which showed an initially small but long-lasting increase after deprivation, and may indicate a change produced by the intervening revitalization of the AA line.
那些至少有几周时间能够接触到乙醇的大鼠,在停止接触一周或更长时间后,通常会在重新接触乙醇的头几天饮用更多的酒。这种酒精剥夺效应现在在25只雄性Long-Evans大鼠中再次出现,但在21只重饮酒的AA系雄性大鼠中未出现。目前在F51代AA大鼠中获得的结果与之前在F32代AA大鼠中获得的结果不同,F32代AA大鼠在剥夺后最初显示出较小但持续时间长的增加,这可能表明AA系的中间复兴产生了变化。