Suppr超能文献

入侵植物(大米草)提取物的抗氧化、胰脂肪酶抑制和酪氨酸酶抑制活性

Antioxidant, Pancreatic Lipase Inhibitory, and Tyrosinase Inhibitory Activities of Extracts of the Invasive Plant (Cord-Grass).

作者信息

Kim Geum Jin, Park Songhee, Kim Eonmi, Kwon Hyukbean, Park Hae-Jin, Nam Joo-Won, Roh Seong-Soo, Choi Hyukjae

机构信息

College of Pharmacy, Yeungnam University, Gyeongsan, Gyeongsangbukdo 38541, Korea.

Research Institute of Cell Culture, Yeungnam University, Gyeongsan, Gyeongsangbukdo 38541, Korea.

出版信息

Antioxidants (Basel). 2021 Feb 4;10(2):242. doi: 10.3390/antiox10020242.

Abstract

Since 2016, the invasive halophyte has been colonizing mudflats along the western coast of South Korea. In order to minimize costs on expansion management and waste-treatment of collected biomass, the potential application of the collected biomass of was investigated. Ethanolic extracts and subfractions thereof (hexanes, methylene chloride, ethyl acetate, 1-butanol, and water-soluble) of the aerial and belowground parts of showed free radical-scavenging [2,2-diphenyl-1-picrylhydrazyl (DPPH), and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS)], tyrosinase inhibitory, and pancreatic lipase inhibitory activities. An ethyl acetate fraction derived from aerial parts (EA-a) showed the most potent radical-scavenging and pancreatic lipase inhibitory activities, whereas tyrosinase inhibition was mainly observed in the methylene chloride soluble fractions (MC-bg) and other lipophilic fractions (ethyl acetate and hexanes layers) obtained from belowground parts. The major EA-a compound isolated and identified was 1,3-di---feruloyl quinic acid () based on spectroscopic analysis, whereas the two major MC-bg compounds were identified as -hydroxybenzaldehyde () and --feruloyltyramine (). Compounds and scavenged both DPPH and ABTS radicals, whereas and inhibited pancreatic lipase activity. These results indicate that extracts and fractions of have antioxidant, anti-obesity, and whitening properties with potential pharmaceutical, cosmeceutical, and functional food applications.

摘要

自2016年以来,这种入侵性盐生植物一直在韩国西海岸的泥滩上定殖。为了尽量减少扩张管理成本和收集生物质的废物处理成本,对收集的生物质的潜在应用进行了研究。该植物地上和地下部分的乙醇提取物及其亚组分(己烷、二氯甲烷、乙酸乙酯、正丁醇和水溶性组分)表现出自由基清除活性[2,2-二苯基-1-苦基肼(DPPH)和2,2'-偶氮二(3-乙基苯并噻唑啉-6-磺酸)(ABTS)]、酪氨酸酶抑制活性和胰脂肪酶抑制活性。来自地上部分的乙酸乙酯组分(EA-a)表现出最强的自由基清除和胰脂肪酶抑制活性,而酪氨酸酶抑制作用主要在从地下部分获得的二氯甲烷可溶组分(MC-bg)和其他亲脂性组分(乙酸乙酯和己烷层)中观察到。基于光谱分析,从EA-a中分离并鉴定出的主要化合物是1,3-二-O-阿魏酰奎宁酸(),而MC-bg中的两种主要化合物被鉴定为对羟基苯甲醛()和对香豆酰酪胺()。化合物和清除了DPPH和ABTS自由基,而和抑制了胰脂肪酶活性。这些结果表明,该植物的提取物和组分具有抗氧化、抗肥胖和美白特性,在制药、药妆和功能性食品领域具有潜在应用价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/527f/7914639/5ddcbc6d91a4/antioxidants-10-00242-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验