Environmental Medicine, University of Southern Denmark, Denmark.
Department of Obstetrics and Gynaecology, Odense University Hospital, Denmark.
Scand J Public Health. 2022 May;50(3):355-361. doi: 10.1177/1403494821990284. Epub 2021 Feb 8.
Due to new evidence on fluoride neurotoxicity during early life, this study examined maternal exposure to fluoride through tea consumption in a low-fluoride region and measured fluoride releases from commercially available teas (tea bags and loose teas) to determine the need to limit fluoride exposure.
Maternal urine fluoride (MUF) concentrations were measured in spot urine samples (=118) from first-trimester pregnant women and in prepared tea infusions made with deionised water from 33 brand teas and 57 loose-tea products, as determined by the direct method of using a fluoride-selective electrode.
The fluoride concentration in the local drinking water supplies ranged from 0.10 to 0.18 mg/L, and the creatinine-adjusted MUF ranged from 0.09 to 1.57 mg/L. Seventeen per cent of the women were daily tea drinkers, and their MUFs were higher than those with no consumption (=0.002). The fluoride concentration from tea bags ranged from 0.34 to 2.67 mg/L, while loose teas showed 0.72-4.50 mg/L (black), 0.56-1.58 mg/L (oolong), 1.28-1.50 mg/L (green), and 0.33-1.17 mg/L (white tea).
由于新的证据表明氟化物在生命早期具有神经毒性，因此本研究检测了低氟地区母亲通过饮茶摄入氟化物的情况，并测量了市售茶（茶包和散装茶）中氟化物的释放量，以确定是否需要限制氟化物暴露。
采用氟离子选择电极的直接法，检测 118 名处于妊娠早期的孕妇的晨尿样本和 33 个品牌的茶包和 57 个散装茶产品的去离子水冲泡茶液中的氟化物浓度，以此来测量母体尿氟浓度（MUF）。
当地饮用水供应中的氟浓度范围为 0.10 至 0.18 毫克/升，肌酐调整后的 MUF 浓度范围为 0.09 至 1.57 毫克/升。17%的女性是日常饮茶者，她们的 MUF 高于不饮茶者（=0.002）。茶包中的氟化物浓度范围为 0.34 至 2.67 毫克/升，而散装茶的氟化物浓度分别为 0.72-4.50 毫克/升（黑茶）、0.56-1.58 毫克/升（乌龙茶）、1.28-1.50 毫克/升（绿茶）和 0.33-1.17 毫克/升（白茶）。
