Department Preventive Medicine and Public Health. University of Navarra, Pamplona-Navarra, Spain.
USF Health Morsani College of Medicine, Scholarly Concentrations Program, Tampa, Florida, USA.
J Hypertens. 2021 Jun 1;39(6):1188-1194. doi: 10.1097/HJH.0000000000002788.
Although available evidence supports the protective effects of walking on hypertension - a major risk factor for cardiovascular disease and stroke - more information is needed in determining whether walking pace independently provides additional hypertension risk reductions. This prospective study determined the association between self-reported walking pace and the incidence of hypertension in the 'Seguimiento Universidad de Navarra' (SUN) cohort in Spain.
Our population sample consisted of 15 357 university graduates initially free of chronic disease or hypertension. During an average follow-up time of 10.9 years, 1673 incident cases of hypertension were observed. Hazard ratios and 95% confidence intervals (95% CIs) for hypertension risk of each walking pace [slow (reference), normal, brisk and very brisk] were estimated using Cox regression models, adjusted for multiple possible confounders. Data were collected from 1999 to 2019, and analysed in 2020.
Participants who walked at a very brisk pace at baseline had a substantially lower risk of developing hypertension during follow-up than those who walked at a slow pace (multivariable-adjusted hazard ratio: 0.64; 95% CI: 0.41-0.99). Inverse associations were observed also for normal (HR: 0.64; 95% CI: 0.46-0.90) and brisk walking pace (0.69; 95% CI: 0.50-0.97) as compared to slow pace, independent of other risk factors.
Our results support that an increase in walking pace, even slightly, is inversely associated with the development of hypertension, independent of total time spent walking and other factors associated with hypertension.
尽管现有证据支持步行对高血压(心血管疾病和中风的主要危险因素)的保护作用,但仍需要更多信息来确定步行速度是否能独立降低高血压风险。本前瞻性研究旨在确定西班牙“纳瓦拉大学随访研究(SUN)”队列中自我报告的步行速度与高血压发病之间的关系。
我们的研究人群由 15357 名最初无慢性病或高血压的大学毕业生组成。在平均 10.9 年的随访期间,观察到 1673 例高血压新发病例。使用 Cox 回归模型,调整了多种可能的混杂因素,估计了每种步行速度(慢步(参考)、正常、轻快和非常轻快)的高血压风险的风险比和 95%置信区间(95%CI)。数据于 1999 年至 2019 年收集,并于 2020 年进行分析。
与慢步相比,基线时快步走的参与者在随访期间发生高血压的风险显著降低(多变量调整后的危险比:0.64;95%CI:0.41-0.99)。与慢步相比,正常(HR:0.64;95%CI:0.46-0.90)和快步(HR:0.69;95%CI:0.50-0.97)也存在反向关联,独立于其他危险因素。
我们的研究结果表明,即使步行速度略有增加,也与高血压的发生呈负相关,这与总的步行时间和其他与高血压相关的因素无关。