Raimondi E, Talarico D, Moro L, Rutter W J, Della Valle G, De Carli L
Dipartimento di Genetica e Microbiologia A. Buzzati-Traverso, Università di Pavia, Italy.
Cytogenet Cell Genet. 1988;47(1-2):98-9. doi: 10.1159/000132518.
In order to determine the subchromosomal location of the gene for human placental alkaline phosphatase (ALPP; EC 3.1.3.1.), a cDNA probe encompassing most of the ALPP translated sequences was hybridized in situ to metaphase chromosomes. Our results confirm previous assignment of the gene to chromosome 2 and allow its regional mapping to band q37.
为了确定人胎盘碱性磷酸酶(ALPP;EC 3.1.3.1.)基因的亚染色体定位,将一个包含大部分ALPP翻译序列的cDNA探针与中期染色体进行原位杂交。我们的结果证实了该基因先前被定位于2号染色体,并将其区域定位到q37带。