通过原位杂交将人胎盘碱性磷酸酶基因（ALPP）定位到2q37区域。
Regional mapping of the human placental alkaline phosphatase gene (ALPP) to 2q37 by in situ hybridization.
作者信息
Raimondi E, Talarico D, Moro L, Rutter W J, Della Valle G, De Carli L
机构信息
Dipartimento di Genetica e Microbiologia A. Buzzati-Traverso, Università di Pavia, Italy.
出版信息
Cytogenet Cell Genet. 1988;47(1-2):98-9. doi: 10.1159/000132518.
PMID:3356175
Abstract
In order to determine the subchromosomal location of the gene for human placental alkaline phosphatase (ALPP; EC 3.1.3.1.), a cDNA probe encompassing most of the ALPP translated sequences was hybridized in situ to metaphase chromosomes. Our results confirm previous assignment of the gene to chromosome 2 and allow its regional mapping to band q37.
摘要
为了确定人胎盘碱性磷酸酶（ALPP；EC 3.1.3.1.）基因的亚染色体定位，将一个包含大部分ALPP翻译序列的cDNA探针与中期染色体进行原位杂交。我们的结果证实了该基因先前被定位于2号染色体，并将其区域定位到q37带。
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