在斯普拉格-道利（Hsd:Sprague Dawley SD）大鼠中进行的毒理学和致癌性研究，这些大鼠暴露于手机使用的频率（900兆赫兹）和调制方式（GSM和CDMA）的全身射频辐射下。
Toxicology and carcinogenesis studies in Sprague Dawley (Hsd:Sprague Dawley SD) rats exposed to whole-body radio frequency radiation at a frequency (900 MHz) and modulations (GSM and CDMA) used by cell phones.
机构信息
Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
出版信息
Natl Toxicol Program Tech Rep Ser. 2018 Nov(595). doi: 10.22427/NTP-TR-595.
Abstract
The predominant source of human exposure to radio frequency radiation (RFR) occurs through usage of cellular phone handsets. The Food and Drug Administration nominated cell phone RFR emission for toxicology and carcinogenicity testing in 1999. At that time, animal experiments were deemed crucial because meaningful human exposure health data from epidemiological studies were not available. Male and female Sprague Dawley (Hsd:Sprague Dawley SD) rats were exposed to time-averaged whole-body specific absorption rates of Global System for Mobile Communications (GSM)- or Code Division Multiple Access (CDMA)-modulated cell phone RFR at 900 MHz in utero, during lactation, and after weaning for 28 days or 2 years. Genetic toxicology studies were conducted in rat peripheral blood erythrocytes and leukocytes, brain cells, and liver cells. (Abstract Abridged).
摘要
人类接触射频辐射（RFR）的主要来源是通过使用手机。1999年，美国食品药品监督管理局指定对手机的射频辐射发射进行毒理学和致癌性测试。当时，动物实验被认为至关重要，因为无法从流行病学研究中获得有意义的人类接触健康数据。将雄性和雌性斯普拉格-道利（Hsd:Sprague Dawley SD）大鼠在子宫内、哺乳期以及断奶后暴露于900MHz全球移动通信系统（GSM）或码分多址（CDMA）调制的手机射频辐射下，时间平均全身比吸收率分别为28天或2年。在大鼠外周血红细胞、白细胞、脑细胞和肝细胞中进行了遗传毒理学研究。（摘要节略）
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