• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

斯洛文尼亚 EQ-5D-Y 值集。

EQ-5D-Y Value Set for Slovenia.

机构信息

Institute for Economic Research, Kardeljeva ploščad 17, 1000, Ljubljana, Slovenia.

出版信息

Pharmacoeconomics. 2021 Apr;39(4):463-471. doi: 10.1007/s40273-020-00994-4. Epub 2021 Feb 10.

DOI:10.1007/s40273-020-00994-4
PMID:33565048
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8009800/
Abstract

BACKGROUND

A value set for the EuroQoL 5-Dimensions (EQ-5D)-Y in Slovenia is not yet available, making the calculation of quality-adjusted life-years (QALYs) for children and adolescents using this generic instrument impossible.

OBJECTIVE

The main objective of our study was to obtain adult preferences towards EQ-5D-Y health states in Slovenia, following the EQ-5D-Y-3L international valuation protocol. The adults were asked to take the perspective of a hypothetical 10-year-old child.

METHOD

A sample of 1074 adults in Slovenia completed an online discrete-choice experiment (DCE) survey on EQ-5D-Y health states. The latent scale issue was addressed by obtaining the value of the anchor (33333) with 200 composite time trade-off (cTTO) interviews. A mixed (random coefficients) logit model was used to estimate the value set.

RESULTS

All the estimated coefficients of the mixed logit model were statistically significant at the 1% level and had an expected negative sign. The most important health dimension in EQ-5D-Y is pain/discomfort, followed by anxiety/depression, usual activities, and mobility, with self-care being the least important health dimension.

CONCLUSIONS

The study addresses an important research gap and presents the EQ-5D-Y value set for Slovenia. At the time of writing, no published value sets are available for the EQ-5D-Y-3L appropriate for use in QALY calculations, making this value set the first EQ-5D-Y value set in the world.

摘要

背景

斯洛文尼亚尚未制定欧洲五维健康量表简表（EQ-5D-Y）的价值量表，因此无法使用该通用量表计算儿童和青少年的质量调整生命年（QALY）。

目的

本研究的主要目的是根据 EQ-5D-Y-3L 国际估值方案，获取斯洛文尼亚成年人对 EQ-5D-Y 健康状况的偏好。要求成年人从一个假设的 10 岁儿童的角度来考虑。

方法

斯洛文尼亚的 1074 名成年人完成了一项关于 EQ-5D-Y 健康状况的在线离散选择实验（DCE）调查。通过对 200 个复合时间权衡（cTTO）访谈获得锚定值（33333）来解决潜在量表问题。采用混合（随机系数）对数模型来估计价值量表。

结果

混合对数模型的所有估计系数在 1%水平上均具有统计学意义，且具有预期的负号。EQ-5D-Y 中最重要的健康维度是疼痛/不适，其次是焦虑/抑郁、日常活动和移动性，自我护理是最不重要的健康维度。

结论

该研究解决了一个重要的研究空白，并提出了斯洛文尼亚的 EQ-5D-Y 价值量表。在撰写本文时，尚无适合用于 QALY 计算的已发表的 EQ-5D-Y-3L 价值量表，因此该价值量表是世界上第一个 EQ-5D-Y 价值量表。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9863/8009800/dcb46698a16b/40273_2020_994_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9863/8009800/03ad8653f4b9/40273_2020_994_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9863/8009800/433978969008/40273_2020_994_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9863/8009800/ab2b43f66cb7/40273_2020_994_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9863/8009800/dcb46698a16b/40273_2020_994_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9863/8009800/03ad8653f4b9/40273_2020_994_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9863/8009800/433978969008/40273_2020_994_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9863/8009800/ab2b43f66cb7/40273_2020_994_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9863/8009800/dcb46698a16b/40273_2020_994_Fig4_HTML.jpg

相似文献

1
EQ-5D-Y Value Set for Slovenia.斯洛文尼亚 EQ-5D-Y 值集。
Pharmacoeconomics. 2021 Apr;39(4):463-471. doi: 10.1007/s40273-020-00994-4. Epub 2021 Feb 10.
2
Estimating an EQ-5D-Y-3L Value Set for Indonesia by Mapping the DCE onto TTO Values.基于离散选择实验（DCE）到时间权衡（TTO）值的映射来估计印度尼西亚的 EQ-5D-Y-3L 值集。
Pharmacoeconomics. 2022 Dec;40(Suppl 2):157-167. doi: 10.1007/s40273-022-01210-1. Epub 2022 Nov 9.
3
Value Set for the EQ-5D-Y-3L in Hungary.匈牙利的 EQ-5D-Y-3L 量表值。
Pharmacoeconomics. 2022 Dec;40(Suppl 2):205-215. doi: 10.1007/s40273-022-01190-2. Epub 2022 Sep 20.
4
Comparison of Adult and Adolescent Preferences Toward EQ-5D-Y-3L Health States.成人与青少年对EQ-5D-Y-3L健康状态的偏好比较。
Value Health. 2021 Sep;24(9):1350-1359. doi: 10.1016/j.jval.2021.03.019. Epub 2021 Jun 25.
5
EQ-5D-Y Value Set for Germany.德国 EQ-5D-Y 量表值。
Pharmacoeconomics. 2022 Dec;40(Suppl 2):217-229. doi: 10.1007/s40273-022-01143-9. Epub 2022 May 23.
6
EQ-5D-5L Value Set for Slovenia.斯洛文尼亚版 EQ-5D-5L 量表值
Pharmacoeconomics. 2023 Nov;41(11):1515-1524. doi: 10.1007/s40273-023-01280-9. Epub 2023 Jun 21.
7
Valuation Survey of EQ-5D-Y Based on the International Common Protocol: Development of a Value Set in Japan.基于国际通用协议的 EQ-5D-Y 评估调查：日本制定价值体系。
Med Decis Making. 2021 Jul;41(5):597-606. doi: 10.1177/0272989X211001859. Epub 2021 Mar 23.
8
Estimating an EQ-5D-Y-3L Value Set for Brazil.估算巴西的 EQ-5D-Y-3L 值集。
Pharmacoeconomics. 2024 Sep;42(9):1047-1063. doi: 10.1007/s40273-024-01404-9. Epub 2024 Jul 2.
9
An EQ-5D-Y-3L Value Set for Belgium.比利时的 EQ-5D-Y-3L 值集。
Pharmacoeconomics. 2022 Dec;40(Suppl 2):169-180. doi: 10.1007/s40273-022-01187-x. Epub 2022 Nov 1.
10
Does Changing the Age of a Child to be Considered in 3-Level Version of EQ-5D-Y Discrete Choice Experiment-Based Valuation Studies Affect Health Preferences?基于 EQ-5D-Y 离散选择实验的价值评估研究中，改变儿童年龄是否会影响健康偏好？
Value Health. 2022 Jul;25(7):1196-1204. doi: 10.1016/j.jval.2022.03.001. Epub 2022 Apr 1.

引用本文的文献

1
The Evolving Landscape of Discrete Choice Experiments in Health Economics: A Systematic Review.健康经济学中离散选择实验的发展态势：一项系统综述
Pharmacoeconomics. 2025 May 21. doi: 10.1007/s40273-025-01495-y.
2
Determining the Content Validity of the EQ-5D-5L, EQ-5D-Y-3L, and CHU9D Instruments for Assessing Generic Child and Adolescent Health-Related Quality of Life: A Qualitative Study.确定用于评估儿童和青少年总体健康相关生活质量的EQ-5D-5L、EQ-5D-Y-3L和CHU9D量表的内容效度：一项定性研究
Patient. 2025 May 16. doi: 10.1007/s40271-025-00743-9.
3
Measurement Properties of the EQ-5D Instruments in Children and Adolescents: A Systematic Review.

本文引用的文献

1
Valuing EQ-5D-Y-3L Health States Using a Discrete Choice Experiment: Do Adult and Adolescent Preferences Differ?使用离散选择实验评估EQ-5D-Y-3L健康状态：成人和青少年的偏好是否不同？
Med Decis Making. 2021 Jul;41(5):584-596. doi: 10.1177/0272989X21999607. Epub 2021 Mar 18.
2
Comparison of online and face-to-face valuation of the EQ-5D-5L using composite time trade-off.运用复合时间权衡法比较 EQ-5D-5L 的线上和面对面估值。
Qual Life Res. 2021 May;30(5):1433-1444. doi: 10.1007/s11136-020-02712-1. Epub 2020 Nov 28.
3
Crosswalk EQ-5D-5L Value Set for Slovenia.
儿童和青少年EQ-5D量表的测量属性：一项系统评价
Appl Health Econ Health Policy. 2025 Apr 19. doi: 10.1007/s40258-025-00953-0.
4
Health state utilities associated with invasive pneumococcal disease, pneumonia, and recurrent acute otitis media in young children.幼儿侵袭性肺炎球菌疾病、肺炎和复发性急性中耳炎相关的健康状态效用值。
Qual Life Res. 2025 Mar;34(3):809-821. doi: 10.1007/s11136-024-03840-8. Epub 2025 Jan 3.
5
Comparison of EQ-5D-Y-3L Utility Scores Using Nine Country-Specific Value Sets in Chinese Adolescents.在中国青少年中使用九种特定国家价值集比较EQ-5D-Y-3L效用评分
Pharmacoeconomics. 2025 Feb;43(2):209-221. doi: 10.1007/s40273-024-01451-2. Epub 2024 Nov 12.
6
Modernizing Newborn Screening in the Genomic Era: Importance of Health-Related Quality of Life.基因组时代新生儿筛查的现代化：健康相关生活质量的重要性。
Pharmacoecon Open. 2024 Nov;8(6):787-792. doi: 10.1007/s41669-024-00528-0. Epub 2024 Oct 3.
7
Transitioning between the EQ-5D youth and adult descriptive systems in a group of adolescents.青少年群体中 EQ-5D 青年版和成人版描述系统间的转换。
J Patient Rep Outcomes. 2024 Aug 12;8(1):93. doi: 10.1186/s41687-024-00770-4.
8
Estimating an EQ-5D-Y-3L Value Set for Brazil.估算巴西的 EQ-5D-Y-3L 值集。
Pharmacoeconomics. 2024 Sep;42(9):1047-1063. doi: 10.1007/s40273-024-01404-9. Epub 2024 Jul 2.
9
The performance of the EQ-5D-Y-5L compared to the EQ-5D-Y-3L in children and adolescents with cerebral palsy (CP).在患有脑瘫（CP）的儿童和青少年中，EQ-5D-Y-5L与EQ-5D-Y-3L的性能比较。
Dialogues Health. 2022 Aug 1;1:100032. doi: 10.1016/j.dialog.2022.100032. eCollection 2022 Dec.
10
Understanding Canadian stakeholders' views on measuring and valuing health for children and adolescents: a qualitative study.了解加拿大利益相关者对儿童和青少年健康测量与估值的看法：一项定性研究。
Qual Life Res. 2024 May;33(5):1415-1422. doi: 10.1007/s11136-024-03618-y. Epub 2024 Mar 5.
斯洛文尼亚的人行横道EQ-5D-5L价值集。
Zdr Varst. 2020 Jun 25;59(3):189-194. doi: 10.2478/sjph-2020-0024. eCollection 2020 Sep.
4
Valuation of EQ-5D-3l Health States in Slovenia: VAS Based and TTO Based Value Sets.斯洛文尼亚EQ-5D-3L健康状态的估值：基于视觉模拟评分法（VAS）和基于时间权衡法（TTO）的价值集
Zdr Varst. 2019 Dec 13;59(1):8-17. doi: 10.2478/sjph-2020-0002. eCollection 2020 Mar.
5
International Valuation Protocol for the EQ-5D-Y-3L.国际 EQ-5D-Y-3L 量表评估协议
Pharmacoeconomics. 2020 Jul;38(7):653-663. doi: 10.1007/s40273-020-00909-3.
6
Feasibility, Validity and Differences in Adolescent and Adult EQ-5D-Y Health State Valuation in Australia and Spain: An Application of Best-Worst Scaling.澳大利亚和西班牙青少年和成人 EQ-5D-Y 健康状态估值的可行性、有效性和差异：最佳最差量表的应用。
Pharmacoeconomics. 2020 May;38(5):499-513. doi: 10.1007/s40273-020-00884-9.
7
EQ-5D-Y as a Health-Related Quality of Life Instrument for Children and Adolescents: The Instrument's Characteristics, Development, Current Use, and Challenges of Developing Its Value Set.EQ-5D-Y 作为儿童和青少年健康相关生活质量的工具：工具的特点、发展、当前应用以及制定其价值体系的挑战。
Value Health. 2019 Jan;22(1):31-37. doi: 10.1016/j.jval.2018.11.001.
8
Overview, Update, and Lessons Learned From the International EQ-5D-5L Valuation Work: Version 2 of the EQ-5D-5L Valuation Protocol.概述、更新以及从国际 EQ-5D-5L 估值工作中吸取的经验教训：EQ-5D-5L 估值议定书第 2 版。
Value Health. 2019 Jan;22(1):23-30. doi: 10.1016/j.jval.2018.05.010. Epub 2019 Jan 2.
9
Valuation of EuroQol Five-Dimensional Questionnaire, Youth Version (EQ-5D-Y) and EuroQol Five-Dimensional Questionnaire, Three-Level Version (EQ-5D-3L) Health States: The Impact of Wording and Perspective.欧洲五维健康量表青年版（EQ-5D-Y）和欧洲五维健康量表 3 级版（EQ-5D-3L）健康状态的估值：措辞和视角的影响。
Value Health. 2018 Nov;21(11):1291-1298. doi: 10.1016/j.jval.2018.05.002. Epub 2018 Aug 8.
10
Valuing the Child Health Utility 9D: Using profile case best worst scaling methods to develop a new adolescent specific scoring algorithm.儿童健康效用9D的评估：运用轮廓案例最佳-最差标度法开发一种新的针对青少年的评分算法。
Soc Sci Med. 2016 May;157:48-59. doi: 10.1016/j.socscimed.2016.03.042. Epub 2016 Mar 31.