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国际 EQ-5D-Y-3L 量表评估协议

International Valuation Protocol for the EQ-5D-Y-3L.

机构信息

Axentiva Solutions, C/Calvario, 271-B 1º IZQ, 38350, Tacoronte, Santa Cruz de Tenerife, Spain.

EuroQol Research Foundation, Rotterdam, The Netherlands.

出版信息

Pharmacoeconomics. 2020 Jul;38(7):653-663. doi: 10.1007/s40273-020-00909-3.

Abstract

The EQ-5D-Y-3L is a generic, health-related, quality-of-life instrument for use in younger populations. Some methodological studies have explored the valuation of children's EQ-5D-Y-3L health states. There are currently no published value sets available for the EQ-5D-Y-3L that are appropriate for use in a cost-utility analysis. The aim of this article was to describe the development of the valuation protocol for the EQ-5D-Y-3L instrument. There were several research questions that needed to be answered to develop a valuation protocol for EQ-5D-Y-3L health states. Most important of these were: (1) Do we need to obtain separate values for the EQ-5D-Y-3L, or can we use the ones from the EQ-5D-3L? (2) Whose values should we elicit: children or adults? (3) Which valuation methods should be used to obtain values for child's health states that are anchored in Full health = 1 and Dead = 0? The EuroQol Research Foundation has pursued a research programme to provide insight into these questions. In this article, we summarized the results of the research programme concluding with the description of the features of the EQ-5D-Y-3L valuation protocol. The tasks included in the protocol for valuing EQ-5D-Y-3L health states are discrete choice experiments for obtaining the relative importance of dimensions/levels and composite time-trade-off for anchoring the discrete choice experiment values on 1 = Full Health and 0 = Dead. This protocol is now available for use by research teams to generate EQ-5D-Y-3L value sets for their countries allowing the implementation of a cost-utility analysis for younger populations.

摘要

EQ-5D-Y-3L 是一种通用的、与健康相关的、适用于年轻人群的生活质量工具。一些方法学研究已经探索了儿童 EQ-5D-Y-3L 健康状况的估值。目前,尚无适用于成本效用分析的 EQ-5D-Y-3L 价值集可供使用。本文的目的是描述 EQ-5D-Y-3L 工具的估值方案的制定过程。为 EQ-5D-Y-3L 健康状况制定估值方案需要回答几个研究问题。其中最重要的问题是:(1)我们是否需要为 EQ-5D-Y-3L 获得单独的价值,还是可以使用 EQ-5D-3L 的价值?(2)我们应该征求谁的意见:儿童还是成人?(3)应该使用哪些估值方法来获得儿童健康状况的价值,这些价值应以完全健康=1 和死亡=0 为基准?欧洲质量生活指数基金会一直在进行一个研究项目,旨在为这些问题提供深入的了解。在本文中,我们总结了研究项目的结果,最后描述了 EQ-5D-Y-3L 估值方案的特点。方案中包括用于获取维度/水平相对重要性的离散选择实验,以及用于将离散选择实验的价值锚定在 1=完全健康和 0=死亡的综合时间权衡实验。该方案现已可供研究团队使用,以便为其国家/地区生成 EQ-5D-Y-3L 价值集,从而为年轻人群实施成本效用分析。

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