Health and Rehabilitation Sciences, University of Western Ontario, London, ON, Canada.
Department of Occupational Therapy, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA.
Mult Scler. 2021 Nov;27(13):2085-2092. doi: 10.1177/1352458521992507. Epub 2021 Feb 10.
Drivers with multiple sclerosis (MS) may experience visual-cognitive impairment that affects their fitness to drive. Due to limitations associated with the on-road assessment, an alternative assessment that measures driving performance is warranted. Whether clinical indicators of on-road outcomes can also predict driving performance outcomes on a driving simulator are not fully understood.
This study examined if deficits in immediate verbal/auditory recall (California Verbal Learning Test-Second Edition; CVLT2-IR) and/or slower divided attention (Useful Field of View™; UFOV2) predicted deficits in operational, tactical, or strategic maneuvers assessed on a driving simulator, in drivers with and without MS.
Participants completed the CVLT2-IR, UFOV2, and a driving simulator assessment of operational, tactical, and strategic maneuvers.
Deficits in immediate verbal/auditory recall and slower divided attention predicted adjustment to stimuli errors, pertaining to tactical maneuvers only, in 36 drivers with MS (vs 20 drivers without MS; (3, 51) = 6.1, = 0.001, = 0.3, ).
The CVLT2-IR and UFOV2 capture the visual and verbal/auditory recall, processing speed, and divided attention required to appropriately adjust to stimuli in a simulated driving environment. Clinicians may use the CVLT2-IR and UFOV2 as precursors to driving performance deficits in drivers with MS.
多发性硬化症（MS）患者可能会出现视觉认知障碍，影响其驾驶能力。由于道路评估存在限制，因此需要一种替代的评估方法来衡量驾驶表现。目前尚不清楚道路评估的临床指标是否也可以预测驾驶模拟器上的驾驶表现结果。
本研究旨在探讨即时言语/听觉回忆（加利福尼亚言语学习测验第二版；CVLT2-IR）和/或注意力分散较慢（有用视野测试；UFOV2）缺陷是否可以预测患有和未患有 MS 的驾驶员在驾驶模拟器上进行的操作、战术和战略操作中存在的缺陷。
参与者完成了 CVLT2-IR、UFOV2 和驾驶模拟器的操作、战术和战略操作评估。
在 36 名 MS 患者（而非 20 名无 MS 患者；(3, 51)=6.1, p=0.001, ɳ²=0.3）中，即时言语/听觉回忆和注意力分散较慢缺陷预测了战术操作中的刺激调整错误。
CVLT2-IR 和 UFOV2 可捕捉到在模拟驾驶环境中适当调整刺激所需的视觉和言语/听觉回忆、处理速度和注意力分散。临床医生可以将 CVLT2-IR 和 UFOV2 作为 MS 患者驾驶表现缺陷的预测指标。
