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高强度力量训练对2型糖尿病老年人习惯性、干预性及总体身体活动水平的影响:GREAT2DO随机对照试验的次要结果

The Effect of High-Intensity Power Training on Habitual, Intervention and Total Physical Activity Levels in Older Adults with Type 2 Diabetes: Secondary Outcomes of the GREAT2DO Randomized Controlled Trial.

作者信息

Mosalman Haghighi Marjan, Mavros Yorgi, Kay Shelley, Simpson Kylie A, Baker Michael K, Wang Yi, Zhao Ren Ru, Meiklejohn Jacinda, Climstein Mike, O'Sullivan Anthony J, De Vos Nathan, Baune Bernhard T, Blair Steven N, Simar David, Singh Nalin, Schlicht Jeffrey, Fiatarone Singh Maria A

机构信息

Faculty of Medicine and Health, University of Sydney, Camperdown 2050, Australia.

Centre for Medical Psychology and Evidence Based Decision Making, Faculty of Medicine, University of Sydney, Camperdown 2050, Australia.

出版信息

Geriatrics (Basel). 2021 Feb 8;6(1):15. doi: 10.3390/geriatrics6010015.

Abstract

BACKGROUND

We examined the effect of power training on habitual, intervention and total physical activity (PA) levels in older adults with type 2 diabetes and their relationship to metabolic control.

MATERIALS AND METHODS

103 adults with type 2 diabetes were randomized to receive supervised power training or sham exercise three times/week for 12 months. Habitual, intervention, and total PA, as well as insulin resistance (HOMA2-IR) and glycosylated hemoglobin (HbA1c), were measured.

RESULTS

Participants were aged 67.9 ± 5.5 yrs, with well-controlled diabetes (HbA1c = 7.1%) and higher than average habitual PA levels compared to healthy peers. Habitual PA did not change significantly over 12 months ( = 0.74), and there was no effect of group assignment on change over time in habitual PA over 0-6 ( = 0.16) or 0-6-12 months ( = 0.51). By contrast, intervention PA, leg press tonnage and total PA increased over both 6- and 12-month timepoints ( = 0.0001), and these changes were significantly greater in the power training compared to the sham exercise group across timepoints ( = 0.0001). However, there were no associations between changes in any PA measures over time and changes in metabolic profile.

CONCLUSION

Structured high-intensity power training may be an effective strategy to enhance overall PA in this high-risk cohort.

摘要

背景

我们研究了力量训练对2型糖尿病老年人的日常、干预和总体身体活动(PA)水平的影响及其与代谢控制的关系。

材料与方法

103名2型糖尿病成年人被随机分为三组,分别接受每周三次、为期12个月的有监督的力量训练或假运动。测量了日常、干预和总体PA水平,以及胰岛素抵抗(HOMA2-IR)和糖化血红蛋白(HbA1c)。

结果

参与者年龄为67.9±5.5岁,糖尿病控制良好(HbA1c = 7.1%),与健康同龄人相比,日常PA水平高于平均水平。12个月内日常PA没有显著变化( = 0.74),在0至6个月( = 0.16)或0至6至12个月( = 0.51)期间,分组对日常PA随时间的变化没有影响。相比之下,干预PA、腿部推举吨位和总体PA在6个月和12个月的时间点均有所增加( = 0.0001),在各个时间点,力量训练组的这些变化显著大于假运动组( = 0.0001)。然而,任何PA测量值随时间的变化与代谢指标的变化之间均无关联。

结论

结构化的高强度力量训练可能是提高这一高危人群总体PA的有效策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f011/7930974/a71edda1c517/geriatrics-06-00015-g001.jpg

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