Said Mohamed M, Rehan Mohamed, El-Sheikh Said M, Zahran Magdy K, Abdel-Aziz Mohamed S, Bechelany Mikhael, Barhoum Ahmed
Chemistry Department, Faculty of Science, Helwan University, Helwan, Cairo 11795, Egypt.
Department of Pretreatment and Finishing of Cellulosic based Textiles. Textile Industries Research Division, National Research Centre, 33 Bohoth Street, Dokki, P.O. Box 12622, Giza 12522, Egypt.
Nanomaterials (Basel). 2021 Feb 8;11(2):429. doi: 10.3390/nano11020429.
Medical textiles have played an increasingly important protection role in the healthcare industry. This study was aimed at improving the conventional cotton gauze for achieving advanced biomedical specifications (coloration, UV-protection, anti-inflammation, and antimicrobial activities). These features were obtained by modifying the cotton gauze fabrics via in-situ precipitation of hydroxyapatite nanoparticles (HAp NP), followed by in-situ photosynthesis of silver (Ag) NPs with ginger oil as a green reductant with anti-inflammation properties. The HAp-Ag NPs coating provides good UV-protection properties. To further improve the HAp and Ag NPs dispersion and adhesion on the surface, the cotton gauze fabrics were modified by cationization with chitosan, or by partial carboxymethylation (anionic modification). The influence of the cationic and anionic modifications and HAp and Ag NPs deposition on the cotton gauze properties (coloration, UV-protection, antimicrobial activities, and water absorption) was thoroughly assessed. Overall, the results indicate that chemical (anionic and cationic) modification of the cotton gauze enhances HAp and Ag NPs deposition. Chitosan can increase biocompatibility and promotes wound healing properties of cotton gauze. Ag NP deposition onto cotton gauze fabrics brought high antimicrobial activities against Candida albicans, Gram-positive and Gram-negative bacteria, and improved UV protection.
医用纺织品在医疗保健行业中发挥着越来越重要的保护作用。本研究旨在改进传统棉纱，以实现先进的生物医学规格（染色、紫外线防护、抗炎和抗菌活性）。这些特性是通过原位沉淀羟基磷灰石纳米颗粒（HAp NP）对棉纱织物进行改性，然后以具有抗炎特性的姜油作为绿色还原剂原位合成银（Ag）纳米颗粒来实现的。HAp-Ag NPs涂层具有良好的紫外线防护性能。为了进一步改善HAp和Ag NPs在表面的分散性和附着力，通过壳聚糖阳离子化或部分羧甲基化（阴离子改性）对棉纱织物进行改性。全面评估了阳离子和阴离子改性以及HAp和Ag NPs沉积对棉纱性能（染色、紫外线防护、抗菌活性和吸水性）的影响。总体而言，结果表明棉纱的化学（阴离子和阳离子）改性增强了HAp和Ag NPs的沉积。壳聚糖可以提高生物相容性并促进棉纱的伤口愈合性能。Ag NPs沉积在棉纱织物上对白色念珠菌、革兰氏阳性菌和革兰氏阴性菌具有很高的抗菌活性，并改善了紫外线防护性能。
